Use of dimethylxanthine theophylline (SpermMobil
Artificial sperm activation
Dimethylxanthine theophylline
ICSI
Obstetric outcomes
Perinatal outcomes
SpermMobil®
Journal
Archives of gynecology and obstetrics
ISSN: 1432-0711
Titre abrégé: Arch Gynecol Obstet
Pays: Germany
ID NLM: 8710213
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
29
05
2019
accepted:
16
09
2019
pubmed:
11
10
2019
medline:
16
5
2020
entrez:
11
10
2019
Statut:
ppublish
Résumé
To evaluate whether the use of a commercially available dimethylxanthine theophylline compound (SpermMobil Artificial sperm activation (ASA) was used when sperm motility after preparation was low or absent in our clinical standard procedure practice. ICSI cycles using either testicular or ejaculated sperm with concentration smaller than 5 million/ml from August 2012 to January 2018 were retrospectively analyzed (n = 815) and divided into two groups, a control group where no ASA was needed and the SpermMobil The fertilization rate was significantly higher in the control group, but pregnancy and implantation rates did not differ significantly. Number of embryos transferred, good quality embryos for ET and number of frozen blastocysts were similar in both groups. Clinical pregnancy loss was significantly reduced in the SpermMobil The use of SpermMobil
Identifiants
pubmed: 31599349
doi: 10.1007/s00404-019-05312-8
pii: 10.1007/s00404-019-05312-8
doi:
Substances chimiques
Theophylline
C137DTR5RG
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM