Cytotoxic Potential of the Coelomic Fluid Extracted from the Sea Cucumber
Holothuria tubulosa
autophagy
breast cancer
cell cycle
cell viability
coelomic fluid
mitochondrial function
Journal
Biology
ISSN: 2079-7737
Titre abrégé: Biology (Basel)
Pays: Switzerland
ID NLM: 101587988
Informations de publication
Date de publication:
09 Oct 2019
09 Oct 2019
Historique:
received:
29
08
2019
revised:
01
10
2019
accepted:
05
10
2019
entrez:
12
10
2019
pubmed:
12
10
2019
medline:
12
10
2019
Statut:
epublish
Résumé
Growing evidence has demonstrated that the extracts of different holothurian species exert beneficial effects on human health. Triple negative breast cancers (TNBC) are highly malignant tumors that present a poor prognosis due to the lack of effective targeted therapies. In the attempt to identify novel compounds that might counteract TNBC cell growth, we studied the effect of the exposure of the TNBC cell line MDA-MB231 to total and filtered aqueous extracts of the coelomic fluid obtained from the sea cucumber
Identifiants
pubmed: 31600896
pii: biology8040076
doi: 10.3390/biology8040076
pmc: PMC6955747
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Università degli Studi di Palermo
ID : FFR 2018
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