Update on current pancreatic treatments: from molecular pathways to treatment.
cancer
gene therapy
pancreatic cancer
stem cells
Journal
Journal of Cancer
ISSN: 1837-9664
Titre abrégé: J Cancer
Pays: Australia
ID NLM: 101535920
Informations de publication
Date de publication:
2019
2019
Historique:
received:
04
05
2019
accepted:
29
07
2019
entrez:
12
10
2019
pubmed:
12
10
2019
medline:
12
10
2019
Statut:
epublish
Résumé
Pancreatic cancer is still diagnosed at a late stage although we have novel diagnostic tools. Pancreatic cancer chemotherapy treatment resistance is observed and therefore novel treatments are in need. Anti-cancer stem cell therapy, combination of chemotherapy and/or radiotherapy with immunotherapy, proteins/enzymes and gene therapy are currently under evaluation. Targeted treatment with tyrosine kinase inhibitors is also administered and novel inhibitors are also under evaluation. In the current review we present recent data from our search within the year 2018.
Identifiants
pubmed: 31602269
doi: 10.7150/jca.36300
pii: jcav10p5162
pmc: PMC6775621
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
5162-5172Informations de copyright
© The author(s).
Déclaration de conflit d'intérêts
Competing Interests: The authors have declared that no competing interest exists.
Références
Radiat Oncol. 2018 Oct 1;13(1):191
pubmed: 30285889
Radiat Oncol J. 2018 Sep;36(3):200-209
pubmed: 30309211
Medicine (Baltimore). 2018 Oct;97(40):e12370
pubmed: 30290595
Hepatobiliary Pancreat Dis Int. 2018 Oct;17(5):461-472
pubmed: 30243879
Ther Clin Risk Manag. 2018 Sep 11;14:1691-1700
pubmed: 30254451
J Pain Res. 2018 Oct 04;11:2169-2178
pubmed: 30323651
Pancreas. 2010 Aug;39(6):707-12
pubmed: 20664470
Transl Oncol. 2019 Jan;12(1):15-23
pubmed: 30245304
J Clin Oncol. 2008 Jun 20;26(18):3063-72
pubmed: 18565894
Cancer. 2017 Jun 1;123(11):1912-1924
pubmed: 28323334
J Geriatr Oncol. 2019 May;10(3):420-426
pubmed: 30236507
Nat Commun. 2018 Oct 15;9(1):4275
pubmed: 30323222
J Cancer. 2018 Sep 8;9(18):3394-3399
pubmed: 30271501
Clin Cancer Res. 2010 Apr 15;16(8):2344-51
pubmed: 20371688
PLoS One. 2013 May 21;8(5):e64268
pubmed: 23704984
J Urol. 2010 Sep;184(3):888-94
pubmed: 20643448
Oncol Rep. 2018 Dec;40(6):3144-3154
pubmed: 30272287
Biopsychosoc Med. 2018 Sep 28;12:13
pubmed: 30288172
J Geriatr Oncol. 2019 Jul;10(4):534-539
pubmed: 30270196
Clin Cancer Res. 2016 Aug 1;22(15):3764-73
pubmed: 26957554
Breast Cancer Res. 2014 Dec 05;16(6):475
pubmed: 25475740
Oncoimmunology. 2018 Sep 25;7(12):e1504727
pubmed: 30524902
Ann Oncol. 2017 Dec 1;28(12):2950-2961
pubmed: 28945842
Anticancer Res. 2006 Sep-Oct;26(5A):3265-73
pubmed: 17094439
Front Oncol. 2016 May 10;6:115
pubmed: 27242955
Gastrointest Endosc. 2019 Feb;89(2):390-398
pubmed: 30222972
Cancer Chemother Pharmacol. 2018 Dec;82(6):1067-1080
pubmed: 30306263
JAMA. 2010 Sep 8;304(10):1073-81
pubmed: 20823433
Mol Ther Nucleic Acids. 2018 Dec 7;13:121-132
pubmed: 30290304
Nanotheranostics. 2018 Aug 25;2(4):371-386
pubmed: 30324083
Front Immunol. 2018 Aug 30;9:1955
pubmed: 30214445
Biochem Pharmacol. 2018 Oct;156:458-466
pubmed: 30222969
Pharmacol Rep. 2018 Dec;70(6):1079-1088
pubmed: 30308458
PLoS One. 2016 Oct 28;11(10):e0165586
pubmed: 27792755
Eur J Endocrinol. 2018 Oct 01;179(4):219-228
pubmed: 30299890
Int J Mol Sci. 2018 Sep 29;19(10):
pubmed: 30274301
Cell Mol Life Sci. 2017 Nov;74(22):4231-4243
pubmed: 28656348
Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):61-72
pubmed: 30267751
JAMA Oncol. 2018 Jul 1;4(7):963-969
pubmed: 29800971
Ann Oncol. 2008 Oct;19(10):1727-33
pubmed: 18515795
J Transl Med. 2015 Jul 22;13:239
pubmed: 26198537
Methods Mol Biol. 2017;1608:343-370
pubmed: 28695521
Sci Rep. 2018 Sep 13;8(1):13759
pubmed: 30214007
Eur J Med Chem. 2018 Oct 5;158:884-895
pubmed: 30253345
Front Immunol. 2018 Sep 07;9:2030
pubmed: 30245691
Cell Death Dis. 2018 Sep 20;9(10):940
pubmed: 30237397
Mol Cancer. 2003 Jan 22;2:14
pubmed: 12605717
Sci Rep. 2018 Sep 18;8(1):14008
pubmed: 30228296
Biochem Biophys Res Commun. 2018 Oct 20;505(1):215-221
pubmed: 30243721
Cancer Lett. 2018 Dec 1;438:174-186
pubmed: 30217561
Onco Targets Ther. 2018 Sep 12;11:5811-5819
pubmed: 30254473
Semin Cancer Biol. 2019 Jun;56:149-167
pubmed: 30314681
Pharmaceuticals (Basel). 2018 Sep 22;11(4):
pubmed: 30248980
J Cancer. 2018 Sep 8;9(18):3417-3426
pubmed: 30271504
Semin Cancer Biol. 2019 Aug;57:19-26
pubmed: 30273655
J Exp Clin Cancer Res. 2018 Sep 21;37(1):236
pubmed: 30241558
Pharmacol Res. 2005 Jul;52(1):109-18
pubmed: 15911339
Oncotarget. 2018 Feb 21;9(19):15144-15156
pubmed: 29599934
HPB (Oxford). 2019 Apr;21(4):444-455
pubmed: 30316625
Radiother Oncol. 2018 Nov;129(2):313-318
pubmed: 30217337
Cancers (Basel). 2018 Sep 26;10(10):
pubmed: 30261620
Am J Cancer Res. 2018 Sep 01;8(9):1812-1822
pubmed: 30323973
Med Oncol. 2018 Oct 4;35(12):151
pubmed: 30284649
Endosc Int Open. 2018 Oct;6(10):E1278-E1282
pubmed: 30302387
Insights Imaging. 2018 Dec;9(6):943-953
pubmed: 30302635
Biochem Biophys Res Commun. 2018 Nov 2;505(3):830-836
pubmed: 30301530
Cancers (Basel). 2012 Sep 06;4(3):873-903
pubmed: 24213471
Mol Cells. 2018 Sep 30;41(9):868-880
pubmed: 30304920
Oncotarget. 2018 Aug 28;9(67):32736-32750
pubmed: 30214681
Oncotarget. 2015 Mar 10;6(7):4717-32
pubmed: 25605248
Eur J Cancer. 2018 Nov;104:62-69
pubmed: 30326370
Clin Transl Med. 2018 Oct 8;7(1):32
pubmed: 30294755
Ann Med Surg (Lond). 2018 Sep 10;34:66-70
pubmed: 30254746
Pancreas. 1996 May;12(4):357-61
pubmed: 8740402
Br J Cancer. 2018 Nov;119(10):1208-1214
pubmed: 30318515
BMC Cancer. 2018 Sep 27;18(1):934
pubmed: 30261853
Eur J Pharm Sci. 2018 Dec 1;125:39-53
pubmed: 30223034
Biochem Biophys Res Commun. 2018 Nov 10;505(4):1077-1083
pubmed: 30314698
Cells. 2018 Oct 05;7(10):
pubmed: 30301152
J Control Release. 2018 Nov 28;290:1-10
pubmed: 30287265
HPB (Oxford). 2019 Apr;21(4):413-418
pubmed: 30293869
Cancer Radiother. 2018 Dec;22(8):754-762
pubmed: 30322818
Iran J Med Sci. 2018 Sep;43(5):533-540
pubmed: 30214106
Clin Cancer Res. 2015 Aug 1;21(15):3561-8
pubmed: 25695692
Biochim Biophys Acta Mol Cell Res. 2018 Dec;1865(12):1914-1923
pubmed: 30296496
J Exp Clin Cancer Res. 2018 Oct 3;37(1):240
pubmed: 30285798
Int J Mol Sci. 2018 Oct 12;19(10):
pubmed: 30321986
Molecules. 2018 Oct 11;23(10):
pubmed: 30314360
Gastroenterology. 2019 Jan;156(1):108-118.e4
pubmed: 30240661