cgmanalysis: An R package for descriptive analysis of continuous glucose monitor data.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2019
Historique:
received: 26 04 2019
accepted: 22 09 2019
entrez: 12 10 2019
pubmed: 12 10 2019
medline: 11 3 2020
Statut: epublish

Résumé

Continuous glucose monitoring (CGM) is an essential part of diabetes care. Real-time CGM data are beneficial to patients for daily glucose management, and aggregate summary statistics of CGM measures are valuable to direct insulin dosing and as a tool for researchers in clinical trials. Yet, the various commercial systems still report CGM data in disparate, non-standard ways. Accordingly, there is a need for a standardized, free, open-source approach to CGM data management and analysis. A package titled cgmanalysis was developed in the free programming language R to provide a rapid, easy, and consistent methodology for CGM data management, summary measure calculation, and descriptive analysis. Variables calculated by our package compare well to those generated by various CGM software, and our functions provide a more comprehensive list of summary measures available to clinicians and researchers. Consistent handling of CGM data using our R package may facilitate collaboration between research groups and contribute to a better understanding of free-living glucose patterns.

Identifiants

pubmed: 31603912
doi: 10.1371/journal.pone.0216851
pii: PONE-D-19-11955
pmc: PMC6788735
doi:

Substances chimiques

Blood Glucose 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0216851

Subventions

Organisme : NIDDK NIH HHS
ID : K12 DK094712
Pays : United States
Organisme : NIDDK NIH HHS
ID : K23 DK116720
Pays : United States

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

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pubmed: 18929686
Diabetes Care. 2019 Mar;42(3):400-405
pubmed: 30352896
Diabetes Technol Ther. 2013 Feb;15(2):172-9
pubmed: 23268584
Bioinformatics. 2018 May 1;34(9):1609-1611
pubmed: 29315360
Pediatr Diabetes. 2018 Nov;19(7):1271-1275
pubmed: 29923262
Diabetes Care. 2017 Dec;40(12):1631-1640
pubmed: 29162583
Diabetes Care. 2018 Nov;41(11):2275-2280
pubmed: 30224348
Diabetes Technol Ther. 2011 Sep;13(9):921-8
pubmed: 21714681
Diabetes Technol Ther. 2011 Mar;13(3):296-302
pubmed: 21291334
Diabetes Technol Ther. 2014 Feb;16(2):72-5
pubmed: 24191760

Auteurs

Tim Vigers (T)

Section of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
Barbara Davis Center, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado, United States of America.

Christine L Chan (CL)

Section of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.

Janet Snell-Bergeon (J)

Barbara Davis Center, University of Colorado School of Medicine, Aurora, Colorado, United States of America.

Petter Bjornstad (P)

Section of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.

Philip S Zeitler (PS)

Section of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.

Gregory Forlenza (G)

Barbara Davis Center, University of Colorado School of Medicine, Aurora, Colorado, United States of America.

Laura Pyle (L)

Section of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
Barbara Davis Center, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado, United States of America.

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Classifications MeSH