Weight-loss with activation of brown fat: Suspect pheochromocytoma.
Adipose Tissue, Brown
/ pathology
Adrenal Gland Neoplasms
/ diagnosis
Adrenalectomy
Catecholamines
/ urine
Female
Humans
Hypertension
Lymphatic Metastasis
/ pathology
Middle Aged
Neoplasm Metastasis
/ diagnosis
Pheochromocytoma
/ diagnosis
Positron-Emission Tomography
Sweating
Tomography, X-Ray Computed
Weight Loss
Brown adipose tissue
Pheochromocytoma
Phéochromocytome
TEP-18-FDG
Tissu adipeux brun
Journal
Annales d'endocrinologie
ISSN: 2213-3941
Titre abrégé: Ann Endocrinol (Paris)
Pays: France
ID NLM: 0116744
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
21
12
2018
revised:
19
04
2019
accepted:
16
06
2019
pubmed:
14
10
2019
medline:
14
4
2020
entrez:
14
10
2019
Statut:
ppublish
Résumé
Excess catecholamine stimulates heat production in brown adipose tissue (BAT). Activation of BAT can be detected in patients presenting pheochromocytoma. A 58-year-old female patient sought medical advice due to 13 kg weight loss over 2 years accompanied by sweating and high blood pressure. Thoracic-abdominal-pelvic CT-scan revealed a solid 40 mm mass in the left adrenal compartment with peri-adrenal nodules and a solid 80 mm mass at the lower end of the right kidney. Brown fat activation may mislead diagnosis of pheochromocytoma, suggesting multi-metastatic extra-adrenal tumor, if clinicians are not aware of it.
Identifiants
pubmed: 31606198
pii: S0003-4266(19)30089-7
doi: 10.1016/j.ando.2019.06.004
pii:
doi:
Substances chimiques
Catecholamines
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
314-318Informations de copyright
Copyright © 2019. Published by Elsevier Masson SAS.