Severe Anti-
Epstein-Barr virus
anti-NMDA receptor encephalitis
autoimmune encephalitis
immunosuppression
liver-transplantation
Journal
Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899
Informations de publication
Date de publication:
2019
2019
Historique:
received:
12
07
2019
accepted:
29
08
2019
entrez:
15
10
2019
pubmed:
15
10
2019
medline:
15
10
2019
Statut:
epublish
Résumé
Anti-NMDA receptor encephalitis is a rare and often therapy-responsive autoimmune disease that usually affects young adults and causes neuropsychiatric symptoms. Here, we describe a 69-year-old patient who developed anti-NMDA receptor encephalitis while being under adequate immunosuppressive therapy following liver transplantation. Although a broad spectrum of different immunotherapies was applied and anti-NMDA receptor antibody titers gradually decreased, the clinical course could not be affected positively. Autoimmune encephalitis after transplantation is only described in a few cases and not well-recognized. Our case adds further evidence for anti-NMDA receptor encephalitis as the cause of neuropsychiatric symptoms even under immunosuppressive therapy in a post-transplant setting.
Identifiants
pubmed: 31608003
doi: 10.3389/fneur.2019.00987
pmc: PMC6773799
doi:
Types de publication
Case Reports
Langues
eng
Pagination
987Informations de copyright
Copyright © 2019 Konen, Schwenkenbecher, Jendretzky, Hümmert, Wegner, Stangel, Sühs and Skripuletz.
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