Evaluation of the Performance of AmpliSeq and SureSelect Exome Sequencing Libraries for Ion Proton.

AmpliSeq SureSelect exome sequencing ion proton sequencer library preparation validation

Journal

Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621

Informations de publication

Date de publication:
2019
Historique:
received: 11 06 2019
accepted: 16 08 2019
entrez: 15 10 2019
pubmed: 15 10 2019
medline: 15 10 2019
Statut: epublish

Résumé

Library preparation for whole-exome sequencing is a critical step serving the enrichment of the regions of interest. For Ion Proton, there are only two exome library preparation methods available, AmpliSeq and SureSelect. Although of major interest, a comparison of the two methods is

Identifiants

pubmed: 31608108
doi: 10.3389/fgene.2019.00856
pmc: PMC6774276
doi:

Types de publication

Journal Article

Langues

eng

Pagination

856

Informations de copyright

Copyright © 2019 Gampawar, Saba, Werner, Schmidt, Müller-Myhsok and Schmidt.

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Auteurs

Piyush Gampawar (P)

Research Unit-Genetic Epidemiology, Gottfried Schatz Research Centre for Cell Signaling, Metabolism and Aging, Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.

Yasaman Saba (Y)

Research Unit-Genetic Epidemiology, Gottfried Schatz Research Centre for Cell Signaling, Metabolism and Aging, Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.

Ulrike Werner (U)

Research Unit-Genetic Epidemiology, Gottfried Schatz Research Centre for Cell Signaling, Metabolism and Aging, Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.

Reinhold Schmidt (R)

Department of Neurology, Clinical Division of Neurogeriatrics, Medical University Graz, Graz, Austria.

Bertram Müller-Myhsok (B)

Max Planck Institute of Psychiatry, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

Helena Schmidt (H)

Research Unit-Genetic Epidemiology, Gottfried Schatz Research Centre for Cell Signaling, Metabolism and Aging, Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.

Classifications MeSH