Fibrinogen levels are associated with bleeding in patients with primary immune thrombocytopenia.

Adult Female Fibrinogen / metabolism Hemorrhage / blood Humans Male Middle Aged Thrombocytopenia / blood
Bleeding fibrinogen platelet primary immune thrombocytopenia thrombocytopenia

Journal

Platelets
ISSN: 1369-1635
Titre abrégé: Platelets
Pays: England
ID NLM: 9208117

Informations de publication

Date de publication:
17 Aug 2020
Historique:
pubmed: 16 10 2019
medline: 29 5 2021
entrez: 16 10 2019
Statut: ppublish

Résumé

Bleeding is the most common clinical symptom and the leading cause of death in patients with primary immune thrombocytopenia (ITP). Our research intends to verify the role of fibrinogen levels as independent determinants of bleeding. We retrospectively analyzed the relationship between fibrinogen levels and bleeding events in 463 patients. Additionally, we confirmed the impact of fibrinogen level on clot firmness in 25 patients via thrombelastography (TEG). Fibrinogen levels (median and inter-quartile range, IQR) were significantly different (

Identifiants

DOI: 10.1080/09537104.2019.1678115 PMID: 31610686
pubmed: 31610686
doi: 10.1080/09537104.2019.1678115
doi:

Substances chimiques

Fibrinogen 9001-32-5

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

763-770

Auteurs

Min Xu (M)

Institute of Haematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei, China.

Lili Luo (L)

Institute of Haematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei, China.

Mengyi Du (M)

Institute of Haematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei, China.

Lu Tang (L)

Institute of Haematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei, China.

Yu Hu (Y)

Institute of Haematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei, China.
Collaborative Innovation Center of Hematology, Huazhong University of Science and Technology , Wuhan, Hubei, China.

Heng Mei (H)

Institute of Haematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei, China.
Collaborative Innovation Center of Hematology, Huazhong University of Science and Technology , Wuhan, Hubei, China.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Fibrinogen levels are associated with bleeding...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Fibrinogène › Fibrinogen levels are associated with bleeding...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Hémorragie › Fibrinogen levels are associated with bleeding...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Fibrinogen levels are associated with bleeding...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Fibrinogen levels are associated with bleeding...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Anomalies des plaquettes › Thrombopénie › Fibrinogen levels are associated with bleeding...