The Neurophysiological Bases of the Impact of Neonicotinoid Pesticides on the Behaviour of Honeybees.
Apis mellifera
acetylcholine
neonicotinoids
neurobiology
plasticity
Journal
Insects
ISSN: 2075-4450
Titre abrégé: Insects
Pays: Switzerland
ID NLM: 101574235
Informations de publication
Date de publication:
14 Oct 2019
14 Oct 2019
Historique:
received:
06
09
2019
revised:
04
10
2019
accepted:
06
10
2019
entrez:
17
10
2019
pubmed:
17
10
2019
medline:
17
10
2019
Statut:
epublish
Résumé
Acetylcholine is the main excitatory neurotransmitter in the honeybee brain and controls a wide range of behaviours that ensure the survival of the individuals and of the entire colony. Neonicotinoid pesticides target this neurotransmission pathway and can thereby affect the behaviours under its control, even at doses far below the toxicity limit. These sublethal effects of neonicotinoids on honeybee behaviours were suggested to be partly responsible for the decline in honeybee populations. However, the neural mechanisms by which neonicotinoids influence single behaviours are still unclear. This is mainly due to the heterogeneity of the exposure pathways, doses and durations between studies. Here, we provide a review of the state of the science in this field and highlight knowledge gaps that need to be closed. We describe the agonistic effects of neonicotinoids on neurons expressing the different nicotinic acetylcholine receptors and the resulting brain structural and functional changes, which are likely responsible for the behavioural alterations reported in bees exposed to neonicotinoids.
Identifiants
pubmed: 31614974
pii: insects10100344
doi: 10.3390/insects10100344
pmc: PMC6835655
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Autonomous Province of Bolzano
ID : B26J16000310003
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