The Hedgehog signal transducer
ABC transporter
Hh pathway
Smo
miR-326
Journal
Cancer management and research
ISSN: 1179-1322
Titre abrégé: Cancer Manag Res
Pays: New Zealand
ID NLM: 101512700
Informations de publication
Date de publication:
2019
2019
Historique:
received:
05
05
2019
accepted:
15
07
2019
entrez:
17
10
2019
pubmed:
17
10
2019
medline:
17
10
2019
Statut:
epublish
Résumé
Multidrug resistance (MDR) and the subsequent disease relapse are the major causes of childhood acute lymphoblastic leukemia (ALL) related death. The Hedgehog (Hh) signaling pathway can contribute to cancer MDR. In the current study, The study included 27 pediatric B-ALL and 16 control bone marrow samples. Quantitative RT-PCR was used to investigate the expression levels of Results showed a significant increase in the Data revealed the possible oncogenic impact of Smo on leukemogenesis and drug resistance in pediatric B-ALL. Upregulation of
Identifiants
pubmed: 31616178
doi: 10.2147/CMAR.S214405
pii: 214405
pmc: PMC6698603
doi:
Types de publication
Journal Article
Langues
eng
Pagination
7621-7630Informations de copyright
© 2019 Sheybani et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
Références
J Cell Physiol. 2018 Aug;233(8):5726-5735
pubmed: 29380372
Anticancer Res. 2014 Nov;34(11):6339-44
pubmed: 25368233
Gene. 2019 Apr 15;692:35-43
pubmed: 30639603
Tumour Biol. 2017 Jul;39(7):1010428317715546
pubmed: 28675107
Cancer Cell. 2008 Sep 9;14(3):238-49
pubmed: 18772113
J Cell Physiol. 2018 Aug;233(8):5642-5654
pubmed: 29154447
Oncogene. 2011 Dec 8;30(49):4874-86
pubmed: 21625222
Breast Cancer Res. 2011 Jun 10;13(3):211
pubmed: 21672282
Cancer Lett. 2015 Dec 1;369(1):124-33
pubmed: 26276718
J Cell Biochem. 2018 Jul;119(7):6024-6032
pubmed: 29630744
Curr Biol. 2007 Jan 23;17(2):165-72
pubmed: 17196391
Cancers (Basel). 2015 Aug 11;7(3):1554-85
pubmed: 26270676
Cancer Cell. 2014 Feb 10;25(2):139-51
pubmed: 24525231
Nat Commun. 2015 Mar 19;6:6604
pubmed: 25790293
Nat Cell Biol. 2013 Apr;15(4):338-44
pubmed: 23548926
Int J Cancer. 2018 Jan 1;142(1):109-120
pubmed: 28905994
Neuro Oncol. 2015 Feb;17(2):243-53
pubmed: 25173582
Nature. 2014 Jul 3;511(7507):90-3
pubmed: 24870236
Oncogene. 2007 Aug 16;26(38):5674-9
pubmed: 17353904
Onco Targets Ther. 2017 Jul 10;10:3373-3380
pubmed: 28744141
Blood. 2012 Dec 13;120(25):5002-13
pubmed: 22821765
Nature. 2018 Jan 25;553(7689):511-514
pubmed: 29342136
Bone Marrow Res. 2013;2013:269107
pubmed: 24416592
Nature. 2009 Apr 9;458(7239):776-9
pubmed: 19169242
Oncogene. 2015 Jul;34(28):3617-26
pubmed: 25263438
Cell Chem Biol. 2017 Mar 16;24(3):252-280
pubmed: 28286127
Crit Rev Oncol Hematol. 2018 Jun;126:100-111
pubmed: 29759551
Cancer. 2017 Jul 1;123(13):2398-2403
pubmed: 28328172
Cancer Biol Ther. 2014 Jan;15(1):35-41
pubmed: 24145140
Int J Cancer. 2013 Aug 1;133(3):579-89
pubmed: 23341351
PLoS One. 2010 Dec 28;5(12):e15262
pubmed: 21203400
Bosn J Basic Med Sci. 2018 Feb 20;18(1):8-20
pubmed: 29274272
Oncol Rep. 2017 Feb;37(2):1261-1269
pubmed: 27959416
Oncologist. 2016 Oct;21(10):1218-1229
pubmed: 27511905
Cancer Biol Ther. 2018 Apr 3;19(4):260-270
pubmed: 27819521
Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14134-9
pubmed: 16968775