Spray-Dried Hierarchical Aggregates of Iron Oxide Nanoparticles and Their Functionalization for Downstream Processing in Biotechnology.
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
08 Oct 2019
08 Oct 2019
Historique:
received:
27
05
2019
accepted:
27
08
2019
entrez:
17
10
2019
pubmed:
17
10
2019
medline:
17
10
2019
Statut:
epublish
Résumé
In this work, the structuring of iron oxide nanoparticles via spray-drying (SD) of aqueous suspensions is investigated, leading to micrometer-sized aggregates with saturation magnetization comparable to that of the individual nanoparticles. Interestingly, the superparamagnetic behavior is retained despite the multicore structure. Modification of the aggregates via the addition of silica nanoparticles to the suspension allows for control of the resulting magnetization by adjusting the iron oxide content. Moreover, the morphology of the produced aggregates is gradually shifted from irregular inflated-like shapes in case of pure iron oxide aggregates to reach spherical structures when bringing the silica content to only 20%. The aggregates with different magnetization can be effectively separated in a simple column with an attached permanent magnet. Functionalization of pure iron oxide aggregates with a previously coupled ligand holding a nitrilotriacetic acid (NTA)-like moiety and subsequent loading with Ni
Identifiants
pubmed: 31616807
doi: 10.1021/acsomega.9b01549
pmc: PMC6787900
doi:
Types de publication
Journal Article
Langues
eng
Pagination
16300-16308Informations de copyright
Copyright © 2019 American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
Références
J Chromatogr A. 2012 Jan 20;1221:57-70
pubmed: 22071423
Soft Matter. 2016 Sep 28;12(36):7435-44
pubmed: 27532509
Nanoscale. 2013 Oct 21;5(20):9455-82
pubmed: 24056756
J Biotechnol. 2017 Jan 20;242:55-63
pubmed: 27888121
Microb Cell Fact. 2016 Feb 09;15:33
pubmed: 26861699
Talanta. 2012 May 30;94:348-52
pubmed: 22608459
Int J Mol Sci. 2015 Aug 20;16(8):19752-68
pubmed: 26307966
Appl Microbiol Biotechnol. 2006 Dec;73(3):495-504
pubmed: 17063328
Chem Soc Rev. 2009 Sep;38(9):2532-42
pubmed: 19690734
Sensors (Basel). 2010;10(1):684-96
pubmed: 22315562
J Mater Sci. 2016 Jan;51(1):513-553
pubmed: 26586919
Methods Enzymol. 2011;500:165-95
pubmed: 21943898
ACS Nano. 2019 May 28;13(5):4972-4979
pubmed: 30897326
ACS Appl Mater Interfaces. 2014 Aug 27;6(16):13607-16
pubmed: 25090244
J Nanopart Res. 2017;19(2):74
pubmed: 28260966
ACS Nano. 2015 Nov 24;9(11):10749-57
pubmed: 26505280
Biotechnol Prog. 2004 May-Jun;20(3):639-54
pubmed: 15176864
Appl Microbiol Biotechnol. 2006 May;70(5):505-16
pubmed: 16496138
Adv Colloid Interface Sci. 2015 Sep;223:40-54
pubmed: 26043877