Factors associated with adverse outcomes during influenza outbreaks in aged care facilities.


Journal

Australian and New Zealand journal of public health
ISSN: 1753-6405
Titre abrégé: Aust N Z J Public Health
Pays: United States
ID NLM: 9611095

Informations de publication

Date de publication:
Feb 2020
Historique:
received: 01 04 2019
revised: 01 06 2019
accepted: 01 07 2019
pubmed: 17 10 2019
medline: 5 3 2020
entrez: 17 10 2019
Statut: ppublish

Résumé

To explore factors associated with adverse outcomes during influenza outbreaks in residential aged care facilities. A retrospective cohort study of all outbreaks reported to three Sydney metropolitan Public Health Units during 2017. A total of 123 outbreaks affected 1,787 residents and 543 staff. Early notification to a Public Health Unit was associated with shorter outbreak duration (p<0.001; B=0.674). Resident attack rates and resident mortality rates were lower in outbreaks notified early, on univariate analysis (p=0.034 and p=0.048 respectively) but not on an adjusted model. Staff attack rates were significantly associated with resident attack rates (p=0.001; B=0.736). Data on staff vaccination rates was incomplete and reported coverage rates were low (median 39%). Resident vaccination coverage ≥95% was associated with shorter outbreak duration in univariate testing but not on an adjusted model. Early public health notification is associated with improved outbreak parameters; sick staff may pose a risk to residents, yet vaccination rates are low. Resident vaccination may also be valuable. Implications for public health: Measures that facilitate early PHU involvement in influenza outbreaks should be implemented, such as compulsory reporting requirements and processes that permit easier notification through technology. Actions that enhance staff and resident vaccination coverage should also be undertaken.

Identifiants

pubmed: 31617654
doi: 10.1111/1753-6405.12933
doi:

Substances chimiques

Influenza Vaccines 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

65-72

Informations de copyright

© 2019 The Authors.

Références

Lansbury LE, Brown CS, Nguyen-Van-Tam JS. Influenza in long-term care facilities. Influenza Other Respir Viruses. 2017;11(5):356-66.
Booy R, Lindley RI, Dwyer DE, Yin JK, Heron LG, Moffatt CR, et al. Treating and preventing influenza in aged care facilities: A cluster randomised controlled trial. PloS One. 2012;7(10):e46509.
Mahmud SM, Thompson LH, Nowicki DL, Plourde PJ. Outbreaks of influenza-like illness in long-term care facilities in Winnipeg, Canada. Influenza Other Respir Viruses. 2013;7(6):1055-61.
Vyas A, Ingleton A, Huhtinen E, Hope K, Najjar Z, Gupta L. Influenza outbreak preparedness: Lessons from outbreaks in residential care facilities in 2014. Commun Dis Intell Q Rep. 2015;39(2):e204-7.
Sayers G, Igoe D, Carr M, Cosgrave M, Duffy M, Crowley B, et al. High morbidity and mortality associated with an outbreak of influenza A(H3N2) in a psycho-geriatric facility. Epidemiol Infect. 2013;141(2):357-65.
Mossad SB. Influenza in long-term care facilities: Preventable, detectable, treatable. Cleve Clin J Med. 2009;76(9):513-21.
Australian Department of Health. 2017 Influenza Season in Australia: A Summary from the National Influenza Surveillance Committee. Canberra (AUST): Government of Australia; 2017.
Vette K, Bareja C, Clark R, Lal A. Establishing thresholds and parameters for pandemic influenza severity assessment, Australia. Bull World Health Organ. 2018;96(8):558-67.
Public Health Act 2010 No 127 (NSW).
Communicable Diseases Network Australia. Guidelines for the Prevention, Control and Public Health Management of Influenza Outbreaks in Residential Care Facilities in Australia. Canberra (AUST): Australian Department of Health; 2017.
Rainwater-Lovett K, Chun K, Lessler J. Influenza outbreak control practices and the effectiveness of interventions in long-term care facilities: A systematic review. Influenza Other Respir Viruses. 2014;8(1):74-82.
O'Connor L, Murphy H, Montague E, Boland M. Epidemiology and management of seasonal influenza outbreaks in long-term care facilities in the health service executive east area of Ireland during the 2013-2014 influenza season. J Immunisation. 2017;1(1):22-32.
Gutierrez-Gonzalez E, Cantero-Escribano JM, Redondo-Bravo L, San Juan-Sanz I, Robustillo-Rodela A, Cendejas-Bueno E, et al. Effect of vaccination, comorbidities and age on mortality and severe disease associated with influenza during the season 2016-2017 in a Spanish tertiary hospital. J Infect Public Health. 2019;12(4):486-91
Demicheli V, Jefferson T, Di Pietrantonj C, Ferroni E, Thorning S, Thomas RE, et al. Vaccines for preventing influenza in the elderly (Cochrane Review). Cochrane Database Syst Rev. 2018;2:CD004876.
Centre for Epidemiology and Evidence. HealthStats NSW. Sydney (AUST): New South Wales Ministry of Health; 2018.
Subelj M. Epidemiologic patterns of influenza outbreaks in institutional settings. Public Health. 2018;155:23-5.
Vaux S, Poujol I, Bonmarin I, Levy-Bruhl D, Desenclos JC. Surveillance of lower respiratory tract infections outbreaks in nursing homes in France. Eur J Epidemiol. 2009;24(3):149-55.
Rosewell A, Chiu C, Lindley R, Dwyer DE, Moffatt CR, Shineberg C, et al. Surveillance for outbreaks of influenza-like illness in the institutionalized elderly. Epidemiol Infect. 2010;138(8):1126-34.
Davis C, Vally H, Bell R, Sheehan F, Beard F. Viral gastrointestinal outbreaks in residential care facilities: An examination of the value of public health unit involvement. Aust N Z J Public Health. 2014;38(2):177-83.
Merritt T, Hope K, Butler M, Durrheim D, Gupta L, Najjar Z, et al. Effect of antiviral prophylaxis on influenza outbreaks in aged care facilities in three local health districts in New South Wales, Australia, 2014. Western Pac Surveill Response J. 2016;7(1):14-20.
Van der Sande MA, Meijer A, Sen-Kerpiclik F, Enserink R, Cools HJ, Overduin P, et al. Effectiveness of post-exposition prophylaxis with oseltamivir in nursing homes: A randomised controlled trial over four seasons. Emerg Themes Epidemiol. 2014;11:13.
Bowles SK, Lee W, Simor AE, Vearncombe M, Loeb M, Tamblyn S, et al. Use of oseltamivir during influenza outbreaks in Ontario nursing homes, 1999-2000. J Am Geriatr Soc. 2002;50(4):608-16.
Zost SJ, Parkhouse K, Gumina ME, Kim K, Diaz Perez S, Wilson PC, et al. Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains. Proc Natl Acad Sci U S A. 2017;114(47):12578-83.
Sullivan SG, Chilver MB, Carville KS, Deng YM, Grant KA, Higgins G, et al. Low interim influenza vaccine effectiveness, Australia, 1 May to 24 September 2017. Euro Surveill. 2017;22(43).
You JH, Wong WC, Ip M, Lee NL, Ho SC. Cost-effectiveness analysis of influenza and pneumococcal vaccination for Hong Kong elderly in long-term care facilities. J Epidemiol Community Health. 2009;63(11):906-11.
Jefferson T, Rivetti D, Rivetti A, Rudin M, Di Pietrantonj C, Demicheli V. Efficacy and effectiveness of influenza vaccines in elderly people: A systematic review. Lancet. 2005;366(9492):1165-74.
Darvishian M, van den Heuvel ER, Bissielo A, Castilla J, Cohen C, Englund H, et al. Effectiveness of seasonal influenza vaccination in community-dwelling elderly people: An individual participant data meta-analysis of test-negative design case-control studies. Lancet Respir Med. 2017;5(3):200-11.
Wendelboe AM, Avery C, Andrade B, Baumbach J, Landen MG. Importance of employee vaccination against influenza in preventing cases in long-term care facilities. Infect Control Hosp Epidemiol. 2011;32(10):990-7.
Lemaitre M, Meret T, Rothan-Tondeur M, Belmin J, Lejonc JL, Luquel L, et al. Effect of influenza vaccination of nursing home staff on mortality of residents: A cluster-randomized trial. J Am Geriatr Soc. 2009;57(9):1580-6.
Hayward AC, Harling R, Wetten S, Johnson AM, Munro S, Smedley J, et al. Effectiveness of an influenza vaccine programme for care home staff to prevent death, morbidity, and health service use among residents: Cluster randomised controlled trial. BMJ. 2006;333(7581):1241.
Kuster SP, Shah PS, Coleman BL, Lam PP, Tong A, Wormsbecker A, et al. Incidence of influenza in healthy adults and healthcare workers: A systematic review and meta-analysis. PloS One. 2011;6(10):e26239.
Guy RJ, Di Natale R, Kelly HA, Lambert SB, Tobin S, Robinson PM, et al. Influenza outbreaks in aged-care facilities: Staff vaccination and the emerging use of antiviral therapy. Med J Aust. 2004;180(12):640-2.
Drinka PJ, Krause PF, Nest LJ, Goodman BM, Gravenstein S. Risk of acquiring influenza B in a nursing home from a culture-positive roommate. J Am Geriatr Soc. 2005;53(8):1437.
Haber MJ, Shay DK, Davis XM, Patel R, Jin X, Weintraub E, et al. Effectiveness of interventions to reduce contact rates during a simulated influenza pandemic. Emerg Infect Dis. 2007;13(4):581-9.
David Z. Roth BH. Social Distancing as a Pandemic Influenza Prevention Measure. Manitoba (CAN): National Collaborating Centre for Infectious Diseases; 2015.
Boonwaat L, Fletcher-Lartey S, Conaty S. Underreporting of influenza outbreaks in aged care facilities in South Western Sydney, Australia, 2014. Western Pac Surveill Response J. 2016;7(1):32-4.
Sydney Local Health DIstrict Media Centre. HealthMatters 2017. Sydney (AUST): State Government of New South Wales; 2017.
Australian Ageing Agenda. New App Helps Staff Identify Flu Outbreaks. Adelaide (AUST): AAA; 2019.
Huhtinen E, Quinn E, Hess I, Najjar Z, Gupta L. Understanding barriers to effective management of influenza outbreaks by residential aged care facilities. Australas J Ageing. 2019;38(1):60-3.
Munier-Marion E, Benet T, Dananche C, Soing-Altach S, Maugat S, Vaux S, et al. Outbreaks of health care-associated influenza-like illness in France: Impact of electronic notification. Am J Infect Control. 2017;45(11):1249-53.
NSW Department of Health. Fact Sheet: Influenza Vaccination Information for Healthcare Workers. Sydney (AUST): State Government of New South Wales; 2018.
Halliday L, Thomson JA, Roberts L, Bowen S, Mead C. Influenza vaccination of staff in aged care facilities in the ACT: How can we improve the uptake of influenza vaccine Aust N Z J Public Health. 2003;27(1):70-5.
Aged Care Quality and Safety Commission. Find a Report. Canberra (AUST): Government of Australia; 2018.

Auteurs

Elaine Tennant (E)

Sydney Local Health District Public Health Unit, New South Wales.
School of Public Health and Community Medicine, University of New South Wales.

Stephanie Fletcher (S)

South Western Sydney Local Health District Public Health Unit, New South Wales.

Sheena Kakar (S)

Sydney Local Health District Public Health Unit, New South Wales.
Nepean Blue Mountains Local Health District Public Health Unit, New South Wales.

Zeina Najjar (Z)

Sydney Local Health District Public Health Unit, New South Wales.

Heidi Lord (H)

South Western Sydney Local Health District Public Health Unit, New South Wales.

Penelope Clark (P)

Western Sydney Local Health District Public Health Unit, New South Wales.

Leena Gupta (L)

Sydney Local Health District Public Health Unit, New South Wales.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH