Prep1 regulates angiogenesis through a PGC-1α-mediated mechanism.
Animals
Cell Movement
/ physiology
Cell Proliferation
/ physiology
Cells, Cultured
Endothelial Cells
/ metabolism
Gene Expression Regulation
/ physiology
Homeodomain Proteins
/ metabolism
Mice
Neovascularization, Pathologic
/ metabolism
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
/ metabolism
PGC-1α inhibition
TALE homeodomain proteins
p160
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
pubmed:
17
10
2019
medline:
9
6
2020
entrez:
17
10
2019
Statut:
ppublish
Résumé
Angiogenesis depends on a delicate balance between the different transcription factors, and their control should be considered necessary for preventing or treating diseases. Pre-B-cell leukemia transcription factor regulating protein 1 (Prep1) is a homeodomain transcription factor that plays a primary role in organogenesis and metabolism. Observations performed in a
Identifiants
pubmed: 31618597
doi: 10.1096/fj.201901230RR
doi:
Substances chimiques
Homeodomain Proteins
0
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
0
Pknox1 protein, mouse
0
Ppargc1a protein, mouse
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
13893-13904Références
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