Acceleration and plateau: two patterns and outcomes of isolated severe fetal cerebral ventricular dilation.


Journal

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
ISSN: 1476-4954
Titre abrégé: J Matern Fetal Neonatal Med
Pays: England
ID NLM: 101136916

Informations de publication

Date de publication:
Sep 2021
Historique:
pubmed: 18 10 2019
medline: 20 7 2021
entrez: 18 10 2019
Statut: ppublish

Résumé

We sought to characterize patterns of This is a retrospective cohort study. ISVM was defined as a sonographic cerebral ventricle atrial with width ≥15 mm in the absence of additional cerebral or other anatomic anomalies. The aim of this study was to characterize two ISVM groups using a receiver operator curve to evaluate the rate of ventricular progression versus need for ventriculoperitoneal (VP) shunt postnatally. Outcomes were compared between the groups using Pearson's chi-squared test, Student Based on the ROC analysis, ventricular growth of ≥3 mm/week versus <3 mm/week distinguished fetuses likely to require a postnatal VP shunt. Fetuses were characterized as accelerators if ventricle growth was ≥3 mm/week at any point and plateaus if <3 mm/week. Accelerators showed a greater average rate of ventricle progression than plateaus (4.1 vs. 1.0 mm/week, respectively, This study characterizes ISVM into two distinct populations based upon the rate of ventricle expansion, differentiated by the need for postnatal shunting. Once a ventricular growth pattern is determined, these distinctions should prove useful in prenatal management and delivery planning.

Identifiants

pubmed: 31619098
doi: 10.1080/14767058.2019.1677590
pmc: PMC7324013
mid: NIHMS1542783
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3014-3020

Subventions

Organisme : NIDDK NIH HHS
ID : K23 DK119949
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001079
Pays : United States

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Auteurs

Christina J Ge (CJ)

Wayne State University School of Medicine, Detroit, MI, USA.

Rosa M Polan (RM)

Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Kristin W Baranano (KW)

Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Irina Burd (I)

Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Ahmet A Baschat (AA)

Center for Fetal Therapy, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Karin J Blakemore (KJ)

Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Edward S Ahn (ES)

Department of Pediatric Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Eric B Jelin (EB)

Department of Pediatric Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Angie C Jelin (AC)

Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.

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Classifications MeSH