Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
03 Oct 2019
Historique:
received: 20 08 2019
revised: 26 09 2019
accepted: 29 09 2019
entrez: 19 10 2019
pubmed: 19 10 2019
medline: 7 3 2020
Statut: epublish

Résumé

This randomized, placebo-controlled, crossover, and double-blind trial aimed to examine the possible effects of four weeks L-theanine administration on stress-related symptoms and cognitive functions in healthy adults. Participants were 30 individuals (nine men and 21 women; age: 48.3 ± 11.9 years) who had no major psychiatric illness. L-theanine (200 mg/day) or placebo tablets were randomly and blindly assigned for four-week administration. For stress-related symptoms, Self-rating Depression Scale, State-Trait Anxiety Inventory-trait, and Pittsburgh Sleep Quality Index (PSQI) scores decreased after L-theanine administration (

Identifiants

pubmed: 31623400
pii: nu11102362
doi: 10.3390/nu11102362
pmc: PMC6836118
pii:
doi:

Substances chimiques

Glutamates 0
Placebos 0
theanine 8021PR16QO

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Funding received from Taiyo Kagaku Co., Ltd., Mie, Japan.
ID : None

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Auteurs

Shinsuke Hidese (S)

Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-Higashi, Kodaira, Tokyo 187-8502, Japan. shidese@ncnp.go.jp.

Shintaro Ogawa (S)

Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-Higashi, Kodaira, Tokyo 187-8502, Japan. sogawa@ncnp.go.jp.

Miho Ota (M)

Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-Higashi, Kodaira, Tokyo 187-8502, Japan. ota@ncnp.go.jp.

Ikki Ishida (I)

Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-Higashi, Kodaira, Tokyo 187-8502, Japan. iishida@ncnp.go.jp.

Zenta Yasukawa (Z)

Department of Research and Development, Nutrition Division, Taiyo Kagaku Co. Ltd, 1-3, Takara-machi, Yokkaichi, Mie 510-0844, Japan. zyasukawa@taiyokagaku.co.jp.

Makoto Ozeki (M)

Department of Research and Development, Nutrition Division, Taiyo Kagaku Co. Ltd, 1-3, Takara-machi, Yokkaichi, Mie 510-0844, Japan. mozeki@taiyokagaku.co.jp.

Hiroshi Kunugi (H)

Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-Higashi, Kodaira, Tokyo 187-8502, Japan. hkunugi@ncnp.go.jp.

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Classifications MeSH