A comprehensive review of topical hemostatic agents: The good, the bad, and the novel.


Journal

The journal of trauma and acute care surgery
ISSN: 2163-0763
Titre abrégé: J Trauma Acute Care Surg
Pays: United States
ID NLM: 101570622

Informations de publication

Date de publication:
01 2020
Historique:
pubmed: 19 10 2019
medline: 25 6 2020
entrez: 19 10 2019
Statut: ppublish

Résumé

Uncontrolled exsanguination remains the leading cause of death for trauma patients, many of whom die in the pre-hospital setting. Without expedient intervention, trauma-associated hemorrhage induces a host of systemic responses and acute coagulopathy of trauma. For this reason, health care providers and prehospital personal face the challenge of swift and effective hemorrhage control. The utilization of adjuncts to facilitate hemostasis was first recorded in 1886. Commercially available products haves since expanded to include topical hemostats, surgical sealants, and adhesives. The ideal product balances efficacy, with safety practicality and cost-effectiveness. This review of hemostasis provides a guide for successful implementation and simultaneously highlights future opportunities.

Identifiants

pubmed: 31626024
doi: 10.1097/TA.0000000000002508
pii: 01586154-202001000-00027
doi:

Substances chimiques

Hemostatics 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e1-e21

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Auteurs

Allison J Tompeck (AJ)

From the Division of Surgical Critical Care, Trauma, and Acute Care Surgery (A.J.T.), University of Arizona-Phoenix, Phoenix, Arizona; Department of General Surgery (A.u.R.G.), SAIMS Hospital, Indore, MP, India; Gel-E, Inc. (M.D.), Phoenix, Arizona; Department of Surgery (S.B.J.), University of Arizona-Phoenix, Phoenix, Arizona; Division of Trauma, Burns, Acute and Critical Care (P.S.B., R.J.W., M.N.), New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, New York; Division of Trauma, Emergency Surgery and Surgical Critical Care (D.K.), Massachusetts General Hospital, Boston, MA; R. Adams Cowley Shock Trauma Center (T.M.S.), University of Maryland Medical Center, Baltimore, Maryland; and Department of Surgery (L.D.B.), Eastern Virginia Medical School, Norfolk, Virginia.

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