Is Doxycycline Appropriate for Routine Treatment of Young Children With Erythema Migrans?


Journal

The Pediatric infectious disease journal
ISSN: 1532-0987
Titre abrégé: Pediatr Infect Dis J
Pays: United States
ID NLM: 8701858

Informations de publication

Date de publication:
11 2019
Historique:
entrez: 19 10 2019
pubmed: 19 10 2019
medline: 29 5 2020
Statut: ppublish

Résumé

The frequency of permanent staining of teeth of young children from doxycycline is thought to be lower than from older tetracyclines, but the precise risk is uncertain. Until more definitive data become available, doxycycline should not be used routinely to treat young children with erythema migrans, a manifestation of Lyme disease for which other antimicrobials are highly effective.

Identifiants

pubmed: 31626045
doi: 10.1097/INF.0000000000002453
pii: 00006454-201911000-00014
pmc: PMC6814264
mid: NIHMS1537284
doi:

Substances chimiques

Anti-Bacterial Agents 0
Doxycycline N12000U13O

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1113-1114

Subventions

Organisme : NCATS NIH HHS
ID : UL1 TR000142
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States

Références

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pubmed: 17029130
N Engl J Med. 1996 Oct 24;335(17):1270-4
pubmed: 8857006
Clin Pediatr (Phila). 2007 Mar;46(2):121-6
pubmed: 17325084
Med J Aust. 1970 Jan 17;1(3):114-9
pubmed: 5434528
Diagn Microbiol Infect Dis. 2019 Mar;93(3):238-242
pubmed: 30442509
J Pediatr. 2015 May;166(5):1246-51
pubmed: 25794784
Chemotherapia (Basel). 1968;13:Suppl:41-50
pubmed: 5666830

Auteurs

Gary P Wormser (GP)

From the Division of Infectious Diseases, New York Medical College, Valhalla, New York.

Franc Strle (F)

Department of Infectious Diseases, University Medical Center Ljubljana, Slovenia.

Eugene D Shapiro (ED)

Departments of Pediatrics and of Epidemiology of Microbial Diseases, Yale University, New Haven, Connecticut.

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Classifications MeSH