The current state of animal models in research: A review.
Animal model
Review
Sham surgery
Simulation
Surgical training
Three Rs
Journal
International journal of surgery (London, England)
ISSN: 1743-9159
Titre abrégé: Int J Surg
Pays: United States
ID NLM: 101228232
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
19
08
2019
revised:
08
10
2019
accepted:
10
10
2019
pubmed:
19
10
2019
medline:
17
3
2020
entrez:
19
10
2019
Statut:
ppublish
Résumé
Animal models have provided invaluable information in the pursuit of medical knowledge and alleviation of human suffering. The foundations of our basic understanding of disease pathophysiology and human anatomy can largely be attributed to preclinical investigations using various animal models. Recently, however, the scientific community, citing concerns about animal welfare as well as the validity and applicability of outcomes, has called the use of animals in research into question. In this review, we seek to summarize the current state of the use of animal models in research.
Identifiants
pubmed: 31627013
pii: S1743-9191(19)30280-8
doi: 10.1016/j.ijsu.2019.10.015
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
9-13Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2019 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.