Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice.

Amino Acids / urine Animals Bone Density / genetics Calcification, Physiologic / genetics Calcitriol / blood Calcium / blood Erythropoietin / blood Female Fibroblast Growth Factor-23 Fibroblast Growth Factors / metabolism Homeostasis / genetics Kidney / metabolism Mice Mice, Inbred C57BL Mice, Transgenic Minerals / metabolism Osteocalcin / blood Phosphates / blood Renal Insufficiency, Chronic / metabolism

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
18 10 2019
Historique:
received: 21 01 2019
accepted: 09 09 2019
entrez: 20 10 2019
pubmed: 20 10 2019
medline: 12 11 2020
Statut: epublish

Résumé

Fibroblast Growth Factor 23 (FGF23) is a phosphaturic factor causing increased renal phosphate excretion as well as suppression of 1,25 (OH)

Identifiants

DOI: 10.1038/s41598-019-51577-z PMID: 31628396 PMC: PMC6802194
pubmed: 31628396
doi: 10.1038/s41598-019-51577-z
pii: 10.1038/s41598-019-51577-z
pmc: PMC6802194
doi:

Substances chimiques

Amino Acids 0
EPO protein, human 0
FGF23 protein, human 0
Fgf23 protein, mouse 0
Minerals 0
Phosphates 0
Osteocalcin 104982-03-8
Erythropoietin 11096-26-7
Fibroblast Growth Factors 62031-54-3
Fibroblast Growth Factor-23 7Q7P4S7RRE
deoxypyridinoline 90032-33-0
Calcitriol FXC9231JVH
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

14989

Références

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1146-55
pubmed: 22006328
Pflugers Arch. 2018 Oct;470(10):1569-1582
pubmed: 29961920
Blood. 2003 Sep 15;102(6):2278-84
pubmed: 12750170
FASEB J. 2018 Jul;32(7):3752-3764
pubmed: 29481308
Acta Anaesthesiol Scand. 2011 Feb;55(2):185-95
pubmed: 21226860
Nephrol Dial Transplant. 2017 Jun 1;32(6):960-968
pubmed: 27836924
Bone. 2017 Jul;100:4-18
pubmed: 27847255
Haematologica. 2017 Nov;102(11):e427-e430
pubmed: 28818868
Nephrol Dial Transplant. 2019 Dec 1;34(12):2057-2065
pubmed: 30007314
J Biol Chem. 2014 Dec 26;289(52):35849-57
pubmed: 25378396
Nat Rev Nephrol. 2009 Aug;5(8):441-9
pubmed: 19546862
J Physiol. 2011 Mar 15;589(Pt 6):1259-64
pubmed: 21282290
Am J Physiol Renal Physiol. 2018 Jan 1;314(1):F132-F139
pubmed: 28877877
Biol Reprod. 2008 Jun;78(6):1049-57
pubmed: 18256329
PLoS One. 2017 Oct 26;12(10):e0186979
pubmed: 29073196
FASEB J. 2015 May;29(5):1890-900
pubmed: 25630969
Trends Endocrinol Metab. 1992 Sep;3(7):263-70
pubmed: 18407110
PLoS One. 2016 Jan 29;11(1):e0147831
pubmed: 26824839
Cytokine. 2017 Jan;89:155-159
pubmed: 26822707
J Bone Miner Res. 2016 Oct;31(10):1877-1887
pubmed: 27082941
Bone. 2014 Nov;68:1-5
pubmed: 25073031
Nature. 2018 Jan 25;553(7689):461-466
pubmed: 29342138
J Clin Invest. 2004 Feb;113(4):561-8
pubmed: 14966565
Kidney Int. 2018 May;93(5):1131-1141
pubmed: 29395333
Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11609-13
pubmed: 11027359
Am J Physiol. 1994 May;266(5 Pt 2):F767-74
pubmed: 7515582
Kidney Int. 2014 Jun;85(6):1340-50
pubmed: 24402093
J Bone Miner Res. 2013 Aug;28(8):1793-803
pubmed: 23505057
Am J Physiol Regul Integr Comp Physiol. 2006 Oct;291(4):R947-56
pubmed: 16690772
Kidney Int. 2018 Jul;94(1):49-59
pubmed: 29735309
Pflugers Arch. 2014 Nov;466(11):2077-87
pubmed: 24557712
Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9805-10
pubmed: 18606998
Annu Rev Physiol. 2013;75:503-33
pubmed: 23398153
Physiol Res. 2015;64(4):439-45
pubmed: 25470522
Blood. 2001 Jan 15;97(2):536-42
pubmed: 11154234
Sci Rep. 2017 Sep 8;7(1):11018
pubmed: 28887454
J Biol Chem. 2014 Apr 4;289(14):9795-810
pubmed: 24509850
Am J Physiol Regul Integr Comp Physiol. 2015 Feb 15;308(4):R330-5
pubmed: 25519735
Science. 2005 Oct 21;310(5747):490-3
pubmed: 16239475
Am J Kidney Dis. 2016 Jan;67(1):133-42
pubmed: 26372086
Nephrol Dial Transplant. 2013 Feb;28(2):352-9
pubmed: 23129826
J Clin Endocrinol Metab. 2018 Jun 1;103(6):2319-2328
pubmed: 29618028
J Am Soc Nephrol. 2011 Nov;22(11):1963-8
pubmed: 21566053
Hepatology. 2013 Dec;58(6):2122-32
pubmed: 23744538
Growth Factors. 2016 Dec;34(5-6):196-202
pubmed: 28095739

Auteurs

Arezoo Daryadel (A)

Institute of Physiology, University of Zurich, Zurich, Switzerland.
Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland.
National Centre for Competence in Research NCCR "Kidney.CH", Zurich, Switzerland.

Luciano Natale (L)

Institute of Physiology, University of Zurich, Zurich, Switzerland.

Petra Seebeck (P)

Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland.
Zurich Integrative Rodent Physiology (ZIRP), University of Zurich, Zurich, Switzerland.

Carla Bettoni (C)

Institute of Physiology, University of Zurich, Zurich, Switzerland.
Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland.
National Centre for Competence in Research NCCR "Kidney.CH", Zurich, Switzerland.

Udo Schnitzbauer (U)

Institute of Physiology, University of Zurich, Zurich, Switzerland.
Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland.
National Centre for Competence in Research NCCR "Kidney.CH", Zurich, Switzerland.

Max Gassmann (M)

Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland.
Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.
Universidad Peruana Cayetano Heredia (UPCH), Lima, Peru.

Carsten A Wagner (CA)

Institute of Physiology, University of Zurich, Zurich, Switzerland. Wagnerca@access.uzh.ch.
Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland. Wagnerca@access.uzh.ch.
National Centre for Competence in Research NCCR "Kidney.CH", Zurich, Switzerland. Wagnerca@access.uzh.ch.
ORCID: 0000-0002-9874-8898

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Eucaryotes › Animaux › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Densité osseuse › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Développement locomoteur › Biominéralisation › Développement osseux › Calcification physiologique › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Lipides › Lipides membranaires › Stérols › Cholécalciférol › Hydroxycholécalciférols › Dihydroxycholécalciférols › Calcitriol › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Facteurs de croissance hématopoïétique › Facteurs de stimulation des colonies › Érythropoïétine › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Facteur-23 de croissance des fibroblastes › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Facteurs de croissance fibroblastique › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Phénomènes physiologiques › Homéostasie › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Produits chimiques inorganiques › Minéraux › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Protéines de liaison au calcium › Ostéocalcine › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du phosphore › Acides du phosphore › Acides phosphoriques › Phosphates › Elevated FGF23 and disordered renal mineral...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Insuffisance rénale chronique › Elevated FGF23 and disordered renal mineral...