Laparoscopic nephrectomy in children with Wilms tumor. Considerations after 10 years of experience.


Journal

Journal of biological regulators and homeostatic agents
ISSN: 0393-974X
Titre abrégé: J Biol Regul Homeost Agents
Pays: Italy
ID NLM: 8809253

Informations de publication

Date de publication:
Historique:
entrez: 22 10 2019
pubmed: 22 10 2019
medline: 12 11 2019
Statut: ppublish

Résumé

Despite laparoscopy in children is considered safe and is routinely used for several procedures, even in neonates and in pediatric oncology, its role in the treatment of pediatric renal tumors is still controversial. This study analyzes the results of laparoscopic nephrectomy for Wilms Tumor (WT) in pediatric age compared with open nephrectomy after 10 years of experience in a single centre. From 1993 in our center of reference for pediatric oncology, 30 patients with WT have been treated. We performed 21 open nephrectomy and in the last 10 years 9 laparoscopic nephrectomy. In all patients treated laparoscopically, the same technique made by the same equip was used. Compared with patients treated by open surgery, we did not find a significant difference in terms of outcome and survival. In the open surgery group, two patients had lung relapse while in the other group there was one local relapse. These three children obtained and maintained a second complete remission with chemotherapy. Open surgery complications were a tumor rupture in two cases, and an episode of pancreatitis 10 days after surgery. In the laparoscopic group, there were two conversions to open surgery not considered as complications but a surgical choice for cystic areas present in the tumor. As far as complications and oncologic outcomes are concerned, both techniques showed similar results. In experienced hands, laparoscopy proves to be an attractive alternative to open surgery for pediatric renal tumors.

Identifiants

pubmed: 31630722
pii: 18

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

95-103. Special Issue: Focus on Pediatric Nephrology

Informations de copyright

Copyright 2019 Biolife Sas. www.biolifesas.org.

Auteurs

M G Scuderi (MG)

Department of Pediatric Surgery "Policlinico-Vittorio Emanuele" of Catania, Italy.

A Di Cataldo (A)

Unit of Pediatric Hematology and Oncology, Department of Clinical and Experimental Medicine, Hospital Policlinico, University of Catania, Catania, Italy.

M Fusco (M)

Department of Human Pathology in Adult and Developmental Age "Gaetano Barresi", Unit of Emergency Pediatrics, University of Messina, Policlinico "G. Martino" Messina, Italy.

P Betta (P)

Neonatal Intensive Care Unit, Policlinico-Vittorio Emanuele" of Catania, Italy.

G Spampinato (G)

Department of Pediatric Surgery "Policlinico-Vittorio Emanuele" of Catania, Italy.

S Arena (S)

Department of Human Pathology of Adult and Childhood "Gaetano Barresi", Unit of Pediatric Surgery, University of Messina, Messina, Italy.

A Centorrino (A)

Department of Human Pathology of Adult and Childhood "Gaetano Barresi", Unit of Pediatric Surgery, University of Messina, Messina, Italy.

R Chimenz (R)

Department of Human Pathology in Adult and Developmental Age "Gaetano Barresi", Unit of Pediatric Nephrology and Rheumatology with Dialysis University of Messina, Policlinico "G. Martino" Messina, Italy.

M Falsaperla (M)

Department of Urology, Vittorio Emanuele Hospital, Catania, Italy.

V Di Benedetto (V)

Department of Pediatric Surgery "Policlinico-Vittorio Emanuele" of Catania, Italy.

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