Non-traumatic cervical artery dissection and ischemic stroke: A narrative review of recent research.

Antithrombotic agents Carotid artery dissection Diagnostic imaging Endovascular procedures Vertebral artery dissection

Journal

Clinical neurology and neurosurgery
ISSN: 1872-6968
Titre abrégé: Clin Neurol Neurosurg
Pays: Netherlands
ID NLM: 7502039

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 19 02 2019
revised: 02 10 2019
accepted: 06 10 2019
pubmed: 22 10 2019
medline: 21 10 2020
entrez: 22 10 2019
Statut: ppublish

Résumé

Cervical artery dissection (CAD) is a leading cause of ischaemic stroke (IS) in young and middle-aged adults. Despite well characterized clinical presentation, the diagnosis of CAD can be quite challenging due to a wide variety of symptoms ranging from minor neck pain to severe neurological symptoms. Invasive diagnostic procedures such as DSA are nowadays being replaced by the sensitive and CAD-specific sequences of MR. The most recent studies confirmed the overall efficacy of antiplatelet and anticoagulant therapies for CAD patients is equivalent, although patients should be qualified for concrete treatment on the basis of recently characterized clinical features. The use of NOAC in CAD-related IS prevention cannot yet be recommended due to the lack of evidences from randomized controlled trials. Endovascular therapies should be considered as the treatment of CAD, especially in the cases of large occlusion or antithrombotic treatment failure. Further research is needed to evaluate the efficacy of new imaging modalities and treatment options. This review summarize the last 5-year development of the diagnosis and treatment for CAD as a causative factor for IS.

Identifiants

pubmed: 31634685
pii: S0303-8467(19)30357-9
doi: 10.1016/j.clineuro.2019.105561
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

105561

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Michał Marciniec (M)

Chair and Department of Neurology, Medical University of Lublin, Poland. Electronic address: lekmarciniec@gmail.com.

Klaudia Sapko (K)

Chair and Department of Neurology, Medical University of Lublin, Poland.

Marcin Kulczyński (M)

Chair and Department of Neurology, Medical University of Lublin, Poland.

Sylwia Popek-Marciniec (S)

Department of Cancer Genetics with Cytogenetics Laboratory, Medical University of Lublin, Poland.

Anna Szczepańska-Szerej (A)

Chair and Department of Neurology, Medical University of Lublin, Poland.

Konrad Rejdak (K)

Chair and Department of Neurology, Medical University of Lublin, Poland.

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