Natural Products in Neurodegenerative Diseases: A Great Promise but an Ethical Challenge.
beneficence
ethics
medical liability
natural products
neurodegenerative diseases
nonmaleficence
patients’ autonomy
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
18 Oct 2019
18 Oct 2019
Historique:
received:
31
08
2019
revised:
09
10
2019
accepted:
16
10
2019
entrez:
23
10
2019
pubmed:
23
10
2019
medline:
4
3
2020
Statut:
epublish
Résumé
Neurodegenerative diseases (NDs) represent one of the most important public health problems and concerns, as they are a growing cause of mortality and morbidity worldwide, particularly in the elderly. Despite remarkable breakthroughs in our understanding of NDs, there has been little success in developing effective therapies. The use of natural products may offer great potential opportunities in the prevention and therapy of NDs; however, many clinical concerns have arisen regarding their use, mainly focusing on the lack of scientific support or evidence for their efficacy and patient safety. These clinical uncertainties raise critical questions from a bioethical and legal point of view, as considerations relating to patient decisional autonomy, patient safety, and beneficial or non-beneficial care may need to be addressed. This paper does not intend to advocate for or against the use of natural products, but to analyze the ethical framework of their use, with particular attention paid to the principles of biomedical ethics. In conclusion, the notable message that emerges is that natural products may represent a great promise for the treatment of many NDs, even if many unknown issues regarding the efficacy and safety of many natural products still remain.
Identifiants
pubmed: 31635296
pii: ijms20205170
doi: 10.3390/ijms20205170
pmc: PMC6834164
pii:
doi:
Substances chimiques
Biological Products
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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