Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report.

Cancer stage Colon cancer Colonoscopy Lynch syndrome Surveillance Survival

Journal

Hereditary cancer in clinical practice
ISSN: 1731-2302
Titre abrégé: Hered Cancer Clin Pract
Pays: Poland
ID NLM: 101231179

Informations de publication

Date de publication:
2019
Historique:
received: 01 06 2019
accepted: 11 09 2019
entrez: 23 10 2019
pubmed: 23 10 2019
medline: 23 10 2019
Statut: epublish

Résumé

We previously reported that in pathogenic mismatch repair ( The Prospective Lynch Syndrome Database (PLSD) that records outcomes of surveillance was examined to determine survival after colon cancer in relation to the time since previous colonoscopy and pathological stage. Only Ninety-nine In

Sections du résumé

BACKGROUND BACKGROUND
We previously reported that in pathogenic mismatch repair (
METHODS METHODS
The Prospective Lynch Syndrome Database (PLSD) that records outcomes of surveillance was examined to determine survival after colon cancer in relation to the time since previous colonoscopy and pathological stage. Only
RESULTS RESULTS
Ninety-nine
CONCLUSIONS CONCLUSIONS
In

Identifiants

pubmed: 31636762
doi: 10.1186/s13053-019-0127-3
pii: 127
pmc: PMC6792227
doi:

Types de publication

Journal Article

Langues

eng

Pagination

28

Subventions

Organisme : Medical Research Council
ID : G0100496
Pays : United Kingdom
Organisme : Department of Health
ID : NIHR-CS-012-009
Pays : United Kingdom

Informations de copyright

© The Author(s). 2019.

Déclaration de conflit d'intérêts

Competing interestsToni Seppälä: a co-owner (20%) of Healthfund Finland Oy (educational and health care services in Finland, not related to patients or scope of this manuscript). Travel costs to a scientific meeting by Medtronic Finland. John Burn: a patent for high speed low cost tumor profiling pending to John Burn and QuantuMDx. All others: None declared.

Références

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Auteurs

Mev Dominguez-Valentin (M)

1Department of Tumor Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway.

Toni T Seppälä (TT)

2Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Helsinki, Finland.
3Clinicum, University of Helsinki, Helsinki, Finland.

Julian R Sampson (JR)

4Division of Cancer and Genetics, Institute of Medical Genetics, Cardiff University School of Medicine, Cardiff, UK.

Finlay Macrae (F)

5The Royal Melbourne Hospital, Melbourne, Australia.
6University of Melbourne, Melbourne, Australia.

Ingrid Winship (I)

5The Royal Melbourne Hospital, Melbourne, Australia.
6University of Melbourne, Melbourne, Australia.

D Gareth Evans (DG)

7University of Manchester & Manchester University Hospitals Foundation Trust, Manchester, UK.

Rodney J Scott (RJ)

University of Newcastle and the Hunter Medical Research Institute, Callaghan, Australia.

John Burn (J)

9University of Newcastle, Newcastle upon Tyne, UK.

Gabriela Möslein (G)

10University Witten-Herdecke, Wuppertal, Germany.

Inge Bernstein (I)

11Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, Denmark.

Kirsi Pylvänäinen (K)

12Central Finland Central Hospital, Education and Research, Jyväskylä, Finland.

Laura Renkonen-Sinisalo (L)

2Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Helsinki, Finland.
13Research Programs Unit, Genome-Scale Biology, University of Helsinki, Helsinki, Finland.

Anna Lepistö (A)

2Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Helsinki, Finland.
13Research Programs Unit, Genome-Scale Biology, University of Helsinki, Helsinki, Finland.

Annika Lindblom (A)

14Karolinska Institutet, Stockholm, Sweden.

John-Paul Plazzer (JP)

5The Royal Melbourne Hospital, Melbourne, Australia.

Douglas Tjandra (D)

6University of Melbourne, Melbourne, Australia.

Huw Thomas (H)

15St Mark's Hospital, Department of Surgery and Cancer, Imperial College London, London, UK.

Kate Green (K)

7University of Manchester & Manchester University Hospitals Foundation Trust, Manchester, UK.

Fiona Lalloo (F)

7University of Manchester & Manchester University Hospitals Foundation Trust, Manchester, UK.

Emma J Crosbie (EJ)

16University of Manchester and St Mary's Hospital, Manchester, UK.

James Hill (J)

7University of Manchester & Manchester University Hospitals Foundation Trust, Manchester, UK.

Gabriel Capella (G)

17Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, Barcelona, Spain.
18Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.

Marta Pineda (M)

17Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, Barcelona, Spain.
18Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.

Matilde Navarro (M)

17Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, Barcelona, Spain.
18Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.

Joan Brunet Vidal (JB)

17Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, Barcelona, Spain.
18Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.

Karina Rønlund (K)

19Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark.

Randi Thyregaard Nielsen (RT)

20Department of Surgery, Regional Hospital West Jutland, Egtved, Denmark.

Mette Yilmaz (M)

21Department of Oncology, Aalborg University Hospital, Aalborg, Denmark.

Louise Laurberg Elvang (LL)

22Department of Pathology, Herlev Gentofte University Hospital, Herlev, Denmark.

Lior Katz (L)

23High Risk and GI Cancer prevention Clinic, Gatro-Oncology Unit, The Department of Gastroenterology, Sheba Medical Center, Ramat Gan, Israel.

Maartje Nielsen (M)

24Leids Universitair Medisch Centrum, Leiden, Netherlands.

Sanne W Ten Broeke (SW)

24Leids Universitair Medisch Centrum, Leiden, Netherlands.

Sigve Nakken (S)

1Department of Tumor Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway.

Eivind Hovig (E)

1Department of Tumor Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway.
25Center for Bioinformatics, Department of Informatics, University of Oslo, Oslo, Norway.

Lone Sunde (L)

26Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.

Matthias Kloor (M)

27Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
28Cooperation Unit Applied Tumor Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Magnus V Knebel Doeberitz (MV)

27Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
28Cooperation Unit Applied Tumor Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Aysel Ahadova (A)

27Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
28Cooperation Unit Applied Tumor Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Noralane Lindor (N)

29Department of Health Sciences Research, Mayo Clinic, Scottsdale, AZ USA.

Verena Steinke-Lange (V)

30Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.
31MGZ- Medical Genetics Center, Munich, Germany.

Elke Holinski-Feder (E)

30Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.
31MGZ- Medical Genetics Center, Munich, Germany.

Jukka-Pekka Mecklin (JP)

32Department of Surgery, Central Finland Central Hospital, Jyväskylä, Finland.
33Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.

Pål Møller (P)

1Department of Tumor Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway.

Classifications MeSH