Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults.
Cytokines
Exercise
Inflammation
Sedentary time
Journal
BMC sports science, medicine & rehabilitation
ISSN: 2052-1847
Titre abrégé: BMC Sports Sci Med Rehabil
Pays: England
ID NLM: 101605016
Informations de publication
Date de publication:
2019
2019
Historique:
received:
26
06
2019
accepted:
24
09
2019
entrez:
23
10
2019
pubmed:
23
10
2019
medline:
23
10
2019
Statut:
epublish
Résumé
Evidence suggests that disrupting prolonged bouts of sitting with short bouts of physical activity can significantly reduce blood glucose and improve insulin sensitivity; however, limited research is available on the impact of such disruptions on inflammation and swelling. The purpose of this study was to determine whether short bouts of exercise performed each hour during a 4 h sitting session were able to negate the effects of Eligible participants ( Concentrations of salivary IL-8 increased during PS (T1: 0.19 ± 0.32; T2: 0.50 ± 1.00 pg/μg of protein) but decreased during DS (T1: 0.41 ± 0.23; T2: 0.22 ± 0.11 pg/μg of protein, It appears that short bouts of exercise significantly reduce swelling in the lower leg and IL-8 levels in the saliva, indicating that even among healthy, active, young adults, disrupting prolonged sitting can significantly reduce swelling and systemic inflammation.
Sections du résumé
BACKGROUND
BACKGROUND
Evidence suggests that disrupting prolonged bouts of sitting with short bouts of physical activity can significantly reduce blood glucose and improve insulin sensitivity; however, limited research is available on the impact of such disruptions on inflammation and swelling. The purpose of this study was to determine whether short bouts of exercise performed each hour during a 4 h sitting session were able to negate the effects of
METHODS
METHODS
Eligible participants (
RESULTS
RESULTS
Concentrations of salivary IL-8 increased during PS (T1: 0.19 ± 0.32; T2: 0.50 ± 1.00 pg/μg of protein) but decreased during DS (T1: 0.41 ± 0.23; T2: 0.22 ± 0.11 pg/μg of protein,
CONCLUSION
CONCLUSIONS
It appears that short bouts of exercise significantly reduce swelling in the lower leg and IL-8 levels in the saliva, indicating that even among healthy, active, young adults, disrupting prolonged sitting can significantly reduce swelling and systemic inflammation.
Identifiants
pubmed: 31636910
doi: 10.1186/s13102-019-0138-4
pii: 138
pmc: PMC6798359
doi:
Types de publication
Journal Article
Langues
eng
Pagination
23Informations de copyright
© The Author(s). 2019.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare that they have no competing interests.
Références
Front Endocrinol (Lausanne). 2017 Apr 24;8:74
pubmed: 28484423
Med Sci Sports Exerc. 2017 Feb;49(2):298-307
pubmed: 28009784
J R Soc Med. 2010 Nov;103(11):447-54
pubmed: 21037335
Mediators Inflamm. 2013;2013:434010
pubmed: 23533306
Diabetologia. 2014 Jul;57(7):1437-45
pubmed: 24817675
Sports Med. 2018 Oct;48(10):2347-2366
pubmed: 30078066
Thromb Res. 2000 Dec 1;100(5):409-12
pubmed: 11150583
Diabetes Care. 2012 May;35(5):976-83
pubmed: 22374636
Brain Behav Immun. 2015 Feb;44:253-69
pubmed: 25205395
Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:4284-4287
pubmed: 28269228
Int J Behav Nutr Phys Act. 2017 Jun 10;14(1):75
pubmed: 28599680
Cytokine. 2016 Jan;77:1-9
pubmed: 26476404
PLoS One. 2016 Apr 26;11(4):e0154075
pubmed: 27115137
Am J Physiol Endocrinol Metab. 2004 May;286(5):E675-85
pubmed: 15102614
Thromb Res. 2007;120(4):497-504
pubmed: 17250877
PLoS One. 2013 Oct 29;8(10):e78350
pubmed: 24205208
Phlebology. 2015 Aug;30(7):486-8
pubmed: 24681523
Lancet. 2016 Sep 24;388(10051):1302-10
pubmed: 27475271
Inform Prim Care. 2009;17(1):55-7
pubmed: 19490774
Med Sci Sports Exerc. 2016 Feb;48(2):175-81
pubmed: 26285021
Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H177-82
pubmed: 27233765
Appl Physiol Nutr Metab. 2017 Jun;42(6):677-680
pubmed: 28264170
Am J Med. 2002 Nov;113(7):580-6
pubmed: 12459405
BMC Public Health. 2014 Apr 09;14:333
pubmed: 24712381
Ind Health. 1997;35(1):36-40
pubmed: 9009499
Nutr Metab Cardiovasc Dis. 2014 Sep;24(9):976-82
pubmed: 24875670
Med Sci Sports Exerc. 2017 Oct;49(10):2119-2130
pubmed: 28514264
Clin Physiol Funct Imaging. 2018 Jan;38(1):93-99
pubmed: 27781404
Int J Sports Med. 2016 Feb;37(2):97-103
pubmed: 26509374
J Physiol. 2012 Mar 1;590(5):1077-84
pubmed: 22289907
Am J Clin Nutr. 2013 Aug;98(2):358-66
pubmed: 23803893
J Gerontol A Biol Sci Med Sci. 2017 Sep 1;72(9):1218-1225
pubmed: 28003373
Health Rep. 2011 Mar;22(1):7-14
pubmed: 21510585
Asian J Sports Med. 2015 Sep;6(3):e24902
pubmed: 26448856
Appl Physiol Nutr Metab. 2007 Oct;32(5):833-9
pubmed: 18059606
Exerc Immunol Rev. 2002;8:6-48
pubmed: 12690937
Med Sci Sports Exerc. 2015 Apr;47(4):843-9
pubmed: 25137367