Evaluation of choroidal hyperreflective dots in acute and chronic central serous chorioretinopathy.


Journal

Indian journal of ophthalmology
ISSN: 1998-3689
Titre abrégé: Indian J Ophthalmol
Pays: India
ID NLM: 0405376

Informations de publication

Date de publication:
11 2019
Historique:
entrez: 23 10 2019
pubmed: 23 10 2019
medline: 29 5 2020
Statut: ppublish

Résumé

To determine the association between hyperreflective dots (HRD) in the choroid and visual acuity and swept-source optical coherence tomography (SS-OCT)-derived structural parameters in central serous chorioretinopathy (CSC). SS-OCT images (single visit) of consecutive patients with CSC were evaluated for the presence of HRDs in the choroid using an automated algorithm and manual measurements of central macular and subfoveal choroidal thicknesses were obtained. 61 eyes of 61 subjects were included in this retrospective study (32 subjects with acute and 29 with chronic CSC). Mean (± SD) choroidal HRD counts in acute and chronic CSC were 139.4 ± 29.9 and 124.9 ± 28.1, respectively (P = 0.04). In acute CSC, HRD was correlated with both age (P = 0.004) and subfoveal choroidal thickness (SFCT) (P = 0.016), but not with visual acuity or other OCT-derived measurements. In chronic CSC, HRD was correlated with central macular thickness (P = 0.011); neurosensory detachment height (P = 0.046); SFCT (P = 0.012). Considering all patients, the presence of HRDS was significantly negatively correlated with age (r = -0.401; P= 0.002) and SFCT (r = -0.332; P= 0.010). HRDs are correlated with both age and SFCT in acute CSC, and with CMT, height of neurosensory detachment and SFCT in chronic CSC. Development of HRDS is associated with the remodelling of chorioretinal structures as previously noted in CSC.

Identifiants

pubmed: 31638047
pii: IndianJOphthalmol_2019_67_11_1850_269624
doi: 10.4103/ijo.IJO_2030_18
pmc: PMC6836603
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1850-1854

Commentaires et corrections

Type : CommentIn

Déclaration de conflit d'intérêts

There are no conflicts of interest.

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Auteurs

Daren Hanumunthadu (D)

Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.

Alexandre Matet (A)

Institut Curie, PSL Research University, Ophthalmology Department; and Université Paris Descartes, Paris, France.

Mohammed Abdul Rasheed (MA)

Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.

Abhilash Goud (A)

Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.

Kiran Kumar Vuppurabina (KK)

Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.

Jay Chhablani (J)

Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.

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Classifications MeSH