Application of 4% chlorhexidine to the umbilical cord stump of newborn infants in lower income countries: a systematic review and meta-analysis.
Chlorhexidine
Cord separation time
Low-income countries
Lower-middle income countries
Neonatal mortality
Newborn infants
Omphalitis
Umbilical cord
Journal
Maternal health, neonatology and perinatology
ISSN: 2054-958X
Titre abrégé: Matern Health Neonatol Perinatol
Pays: England
ID NLM: 101655194
Informations de publication
Date de publication:
2019
2019
Historique:
received:
10
01
2019
accepted:
11
09
2019
entrez:
24
10
2019
pubmed:
24
10
2019
medline:
24
10
2019
Statut:
epublish
Résumé
There are conflicting results from large randomized controlled trials in different populations regarding the effectiveness of topical application of 4% chlorhexidine to the umbilical stump of newborn infants at reducing neonatal mortality. Meta-analysis and systematic review of trials performed in South Asia and Europe support 4% chlorhexidine application to reduce neonatal mortality, whereas trials performed in Sub-Saharan Africa do not. The aim of this review is to determine the effectiveness of 4% chlorhexidine application to the umbilical stump of newborn infants born in lower income countries in order to reduce neonatal mortality when compared with usual cord care.Our search strategy included randomized trials published between January1 Systematic Review Registration: CRD42018109280.
Identifiants
pubmed: 31641528
doi: 10.1186/s40748-019-0111-y
pii: 111
pmc: PMC6796424
doi:
Types de publication
Journal Article
Review
Retracted Publication
Langues
eng
Pagination
16Commentaires et corrections
Type : RetractionIn
Informations de copyright
© The Author(s). 2019.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare that they have no competing interests.
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