Platelet in vitro assays: their correspondence with their in vivo hemostatic potential.
Journal
Transfusion
ISSN: 1537-2995
Titre abrégé: Transfusion
Pays: United States
ID NLM: 0417360
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
07
03
2019
revised:
26
07
2019
accepted:
28
08
2019
pubmed:
24
10
2019
medline:
17
6
2020
entrez:
24
10
2019
Statut:
ppublish
Résumé
Developments during the past few years have resulted in multiple kinds of platelet products for transfusion. This involves different collection methods, containers, preservative solutions, modifications of storage temperatures and durations, and additional treatments such as pathogen reduction. Much experience has been obtained testing these processes in vitro to seek indications of in vivo effectiveness. Availability of an in vitro method that correlated with in vivo effectiveness would be extremely valuable for these different kinds of platelet products and as more innovation in platelet preparation occurs in the future. This report reviews the methods for in vitro platelet testing with a view to their in vivo implications and whether such testing could be helpful in projecting the clinical effectiveness of different platelet products.
Substances chimiques
Hemostatics
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
3783-3793Informations de copyright
© 2019 AABB.
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