[Poisonous plants-a new approach for assessing the risk of poisoning in small children].

Risiko Pflanze – Ein neuer Ansatz zur Einschätzung des Vergiftungsrisikos für Kleinkinder.

Journal

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
ISSN: 1437-1588
Titre abrégé: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Pays: Germany
ID NLM: 101181368

Informations de publication

Date de publication:
Nov 2019
Historique:
pubmed: 24 10 2019
medline: 18 12 2019
entrez: 24 10 2019
Statut: ppublish

Résumé

Plant poisoning in small children (from 0.5 to <6 years of age) is the third most frequent cause for phone contact with a poison center. For prevention of poisonings, a list of poisonous plants that should not be planted close to playgrounds or other places frequently visited by children was published in 2000 by the Bundesanzeiger. This list has been reevaluated and updated by the "Toxicity of Plants" working group of the Committee of the Assessment of Intoxications at the Federal Institute of Risk Assessment (BfR). Relevant plants were taken from a recent publication. A literature search was conducted in PubMed concerning all plant poisonings in children and the toxic ingredients of plants. Also, monographs and the database POISINDEX were integrated in the evaluation. A classification was made for plants that after oral, dermal, or ocular contact of small quantities could cause severe, moderate, mild, or no intoxications in small children. Based on data of exposure and potentially toxic ingredients of the involved plants, a risk assessment was executed, which diverges from other publications because it concerns the actual basic risk of an intoxication. In total, 251 plants were reevaluated. For 11 plants, there was a high risk, for 32 a moderate, for 115 a mild, and for 93 plants no risk of intoxication could be determined. The new assessment of evaluating a toxicity risk for small children on the basis of exposure data and including the toxicity of ingredients allows for a more realistic assessment of the risk of poisoning with outdoor plants. In this way, infant exposure carrying a high risk of intoxication can be identified.

Sections du résumé

BACKGROUND BACKGROUND
Plant poisoning in small children (from 0.5 to <6 years of age) is the third most frequent cause for phone contact with a poison center. For prevention of poisonings, a list of poisonous plants that should not be planted close to playgrounds or other places frequently visited by children was published in 2000 by the Bundesanzeiger. This list has been reevaluated and updated by the "Toxicity of Plants" working group of the Committee of the Assessment of Intoxications at the Federal Institute of Risk Assessment (BfR).
MATERIALS AND METHODS METHODS
Relevant plants were taken from a recent publication. A literature search was conducted in PubMed concerning all plant poisonings in children and the toxic ingredients of plants. Also, monographs and the database POISINDEX were integrated in the evaluation. A classification was made for plants that after oral, dermal, or ocular contact of small quantities could cause severe, moderate, mild, or no intoxications in small children.
RESULTS RESULTS
Based on data of exposure and potentially toxic ingredients of the involved plants, a risk assessment was executed, which diverges from other publications because it concerns the actual basic risk of an intoxication. In total, 251 plants were reevaluated. For 11 plants, there was a high risk, for 32 a moderate, for 115 a mild, and for 93 plants no risk of intoxication could be determined.
CONCLUSION CONCLUSIONS
The new assessment of evaluating a toxicity risk for small children on the basis of exposure data and including the toxicity of ingredients allows for a more realistic assessment of the risk of poisoning with outdoor plants. In this way, infant exposure carrying a high risk of intoxication can be identified.

Identifiants

pubmed: 31642941
doi: 10.1007/s00103-019-03034-5
pii: 10.1007/s00103-019-03034-5
doi:

Types de publication

Journal Article Review

Langues

ger

Sous-ensembles de citation

IM

Pagination

1336-1345

Auteurs

Maren Hermanns-Clausen (M)

Vergiftungs-Informations-Zentrale, Klinik für allgemeine Kinder und Jugendmedizin, Zentrum für Kinder und Jugendmedizin (Departement), Universitätsklinikum Freiburg, Mathildenstr. 1, 79106, Freiburg, Deutschland. maren.hermanns-clausen@uniklinik-freiburg.de.

Hilke Andresen-Streichert (H)

Arbeitsbereich Toxikologie, Institut für Rechtsmedizin, Uniklinik Köln, Köln, Deutschland.

Jörg Pietsch (J)

Abteilung Toxikologische Chemie, Institut für Rechtsmedizin, Technische Universität Dresden, Dresden, Deutschland.

Daniela Acquarone (D)

Giftnotruf, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.

Joan Fuchs (J)

Tox Info Suisse, Assoziiertes Institut der Universität Zürich, Zürich, Schweiz.

Kathrin Begemann (K)

Abteilung Exposition, Bundesinstitut für Risikobewertung, Berlin, Deutschland.

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Classifications MeSH