Polar organization of collagen in human cardiac tissue revealed with polarimetric second-harmonic generation microscopy.
Journal
Biomedical optics express
ISSN: 2156-7085
Titre abrégé: Biomed Opt Express
Pays: United States
ID NLM: 101540630
Informations de publication
Date de publication:
01 Oct 2019
01 Oct 2019
Historique:
received:
20
05
2019
revised:
16
08
2019
accepted:
16
08
2019
entrez:
25
10
2019
pubmed:
28
10
2019
medline:
28
10
2019
Statut:
epublish
Résumé
Polarimetric second-harmonic generation (P-SHG) microscopy is used to characterize the composition and polarity of collagen fibers in various regions of human cardiac tissue. The boundary between the cardiac conduction system and myocardium is shown to possess a distinct composition of collagen compared to other regions in the heart. Moreover, collagen fibers in this region are macroscopically organized in a unipolar arrangement, which may consequently aid in effective propagation of the electrical signal through the cardiac conduction system.
Identifiants
pubmed: 31646027
doi: 10.1364/BOE.10.005025
pii: 367915
pmc: PMC6788612
doi:
Types de publication
Journal Article
Langues
eng
Pagination
5025-5030Informations de copyright
© 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest related to this article.
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