A transdiagnostic model of psychiatric symptom co-occurrence and autism spectrum disorder.
autism spectrum disorder
comorbidity
factorial invariance
transdiagnostic factors
Journal
Autism research : official journal of the International Society for Autism Research
ISSN: 1939-3806
Titre abrégé: Autism Res
Pays: United States
ID NLM: 101461858
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
15
03
2019
revised:
28
08
2019
accepted:
11
09
2019
pubmed:
28
10
2019
medline:
26
1
2021
entrez:
25
10
2019
Statut:
ppublish
Résumé
Understanding whether the co-occurrence of psychiatric symptoms within autism spectrum disorder (ASD) are specific to the ASD diagnosis or reflect similar higher-order patterns observed in both ASD and non-ASD samples, or a confluence of the two, is of critical importance. If similar, it would suggest that comorbid psychiatric conditions among individuals with ASD are not symptoms of specific, non-ASD psychiatric disorders per se, but reflect a general liability to psychopathology associated with ASD. To this end, the current study examined whether the higher-order structure of co-occurring psychiatric symptoms was the same within ASD and non-ASD youth. Parents of clinic-referred youth with (n = 280) and without (n = 943) ASD completed a DSM-IV-referenced psychiatric symptom rating scale. A confirmatory factor analytic framework was used to examine four levels of measurement invariance across groups to determine the extent to which transdiagnostic factors were comparable. Transdiagnostic factors were characterized by symptoms of the same disorders (configural invariance) and the same factor loadings across groups (metric invariance). Furthermore, both groups evidenced equivalent numbers of symptoms of most psychiatric conditions with the notable exceptions of attention deficit hyperactivity disorder (ADHD) and social anxiety (partial strong invariance), which were higher in the ASD sample. It was concluded that disparities in the co-occurrence of psychiatric symptoms between youth with and without ASD may be largely reflective of transdiagnostic factor level differences associated with ASD and not indicative of the ASD diagnosis per se. However, for ADHD and social anxiety, there appears to be some specific associations with the ASD diagnosis. Autism Res 2020, 13: 579-590. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Few transdiagnostic dimensions relate common mental disorder diagnoses with one another. These dimensions explain psychiatric comorbidity (i.e., the finding that many persons possess several disorder diagnoses simultaneously). However, it is unclear if these dimensions differ among children with autism spectrum disorder (ASD), compared with their non-ASD counterparts. The results of this study demonstrate that underlying transdiagnostic dimensions are similar in both ASD and non-ASD children. However, there appear to be ASD-specific differences when it comes to social anxiety and attention deficit hyperactivity disorder.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
579-590Informations de copyright
© 2019 International Society for Autism Research, Wiley Periodicals, Inc.
Références
Achenbach, T. M. (1966). The classification of children's psychiatric symptoms: A factor analytic study. Psychological Monographs: General and Applied, 80(7), 1-37.
Antshel, K. M., Polacek, C., McMahon, M., Dygert, K., Spenceley, L., Dygert, L., … Faisal, F. (2011). Comorbid ADHD and anxiety affect social skills group intervention treatment efficacy in children with autism spectrum disorders. Journal of Developmental and Behavioral Pediatrics, 32, 439-446.
Barlow, D. H., Ellard, K. K., Sauer-Zavala, S., Bullis, J. R., & Carl, J. R. (2014). The origins of neuroticism. Perspectives on Psychological Science, 9(5), 481-496.
Barlow, D. H., Farchione, T. J., Sauer-Zavala, S., Latin, H. M., Ellard, K. K., Bullis, J. R., … Cassiello-Robbins, C. (2017). Unified protocol for transdiagnostic treatment of emotional disorders: Therapist guide. New York, NY: Oxford University Press.
Bentler, P. M., & Bonett, D. G. (1980). Significance tests and goodness of fit in the analysis of covariance structures. Psychological Bulletin, 88, 588-606.
Berument, S. K., Rutter, M., Lord, C., Pickles, A., & Bailey, A. (1999). Autism screening questionnaire: Diagnostic validity. The British Journal of Psychiatry, 175(5), 444-451.
Bradshaw, J. L., & Sheppard, D. M. (2000). The neurodevelopmental frontostriatal disorders: Evolutionary adaptiveness and anomalous lateralization. Brain and Language, 73(2), 297-320.
Byrne, B. M., Shavelson, R. J., & Muthén, B. (1989). Testing for the equivalence of factor covariance and mean structures: The issue of partial measurement invariance. Psychological Bulletin, 105(3), 456-466.
Cheung, G. W., & Rensvold, R. B. (2002). Evaluating goodness-of-fit indexes for testing measurement invariance. Structural Equation Modeling, 9(2), 233-255.
DeVincent, C. J., & Gadow, K. D. (2009). Relative clinical utility of three Child Symptom Inventory-4 scoring algorithms for differentiating children with autism spectrum disorder versus attention-deficit hyperactivity disorder. Autism Research, 2(6), 312-321.
Drabick, D. A., & Gadow, K. D. (2012). Deconstructing oppositional defiant disorder: Clinic-based evidence for an anger/irritability phenotype. Journal of the American Academy of Child & Adolescent Psychiatry, 51(4), 384-393.
Eaton, N. R. (2014). Transdiagnostic psychopathology factors and sexual minority mental health: Evidence of disparities and associations with minority stressors. Psychology of Sexual Orientation and Gender Diversity, 1(3), 244-254.
Eaton, N. R., Keyes, K. M., Krueger, R. F., Balsis, S., Skodol, A. E., Markon, K. E., … Hasin, D. S. (2012). An invariant dimensional liability model of gender differences in mental disorder prevalence: Evidence from a national sample. Journal of Abnormal Psychology, 121(1), 282-288.
Eaton, N. R., Keyes, K. M., Krueger, R. F., Noordhof, A., Skodol, A. E., Markon, K. E., … Hasin, D. S. (2013). Ethnicity and psychiatric comorbidity in a national sample: Evidence for latent comorbidity factor invariance and connections with disorder prevalence. Social Psychiatry and Psychiatric Epidemiology, 48, 701-710.
Eaton, N. R., Krueger, R. F., & Oltmanns, T. F. (2011). Aging and the structure and long-term stability of the internalizing spectrum of personality and psychopathology. Psychology and Aging, 26(4), 987-993.
Eaton, N. R., Rodriguez-Seijas, C., Carragher, N., & Krueger, R. F. (2015). Transdiagnostic factors of psychopathology and substance use disorders: A review. Social Psychiatry and Psychiatric Epidemiology, 50(2), 171-182.
Gadow, K. D. (2015). The symptom inventories: An annotated bibliography. Stony Brook, NY: Checkmate Plus.
Gadow, K. D., DeVincent, C., & Schneider, J. (2008). Predictors of psychiatric symptoms in children with an autism spectrum disorder. Journal of Autism and Developmental Disorders, 38, 1710-1720.
Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2006). ADHD symptom subtypes in children with pervasive developmental disorder. Journal of Autism and Developmental Disorders, 36, 271-283.
Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2005). Comparison of DSM-IV symptoms in elementary school-age children with PDD versus clinic and community samples. Autism, 9(4), 392-415.
Gadow, K. D., & Drabick, D. A. (2012). Anger and irritability symptoms among youth with ODD: Cross-informant versus source-exclusive syndromes. Journal of Abnormal Child Psychology, 40(7), 1073-1085.
Gadow, K. D., & Garman, H. (2018). Social anhedonia in autism spectrum disorder and psychiatry referrals. Journal of Clinical Child and Adolescent Psychology, 9, 1-12. https://doi.org/10.1080/15374416.2018.1539912
Gadow, K. D., Kaat, A. J., & Lecavalier, L. (2013). Relation of symptom-induced impairment with other illness parameters in clinic-referred youth. Journal of Child Psychology and Psychiatry, 54(11), 1198-1207.
Gadow, K. D., Perlman, G., Ramdhany, L., & de Ruiter, J. (2016). Clinical correlates of co-occurring psychiatric and autism spectrum disorder (ASD) symptom-induced impairment in children with ASD. Journal of Abnormal Child Psychology, 44, 129-139.
Gadow, K. D., Schwartz, J., DeVincent, C. J., Strong, G., & Cuva, S. (2008). Clinical utility of autism spectrum disorder scoring algorithms for the Child Symptom Inventory. Journal of Autism and Developmental Disorders, 38(3), 419-427.
Gadow, K. D., & Sprafkin, J. (2005). Child and adolescent symptom inventory-4R. Stony Brook, NY: Checkmate Plus.
Gregorich, S. E. (2006). Do self-report instruments allow meaningful comparisons across diverse population groups? Testing measurement invariance using the confirmatory factor analysis framework. Medical care, 44(11 Suppl 3), S78-S94.
Gotham, K., Unruh, K., & Lord, C. (2015). Depression and its measurement in verbal adolescents and adults with autism spectrum disorder. Autism, 19(4), 491-504.
Greenlee, J. L., Mosley, A. S., Shui, A. M., Veenstra-Vander Weele, J., & Gotham, K. O. (2016). Medical and behavioral correlates of depression history in childrenand adolescents with autism spectrum disorder. Pediatrics, 137(Suppl 2), S105-S114.
Gurney, J. G., McPheeters, M. L., & Davis, M. M. (2006). Parental report of health conditions and health care use among children with and without autism. Archives of Pediatric and Adolescent Medicine, 160, 825-830.
Hallett, V., Ronald, A., Colvert, E., Ames, C., Woodhouse, E., Lietz, S., … Happé, F. (2013). Exploring anxiety symptoms in a large-scale twin study of children with autism spectrum disorders, their co-twins and controls. Journal of Child Psychology and Psychiatry and Allied Disciplines, 54(11), 1176-1185. http://doi.org/10.1111/jcpp.12068
Henderson, H. A., Ono, K. E., McMahon, C. M., Schwartz, C. B., Usher, L. V., & Mundy, P. C. (2015). The costs and benefits of self-monitoring for higher functioning children and adolescents with autism. Journal of Autism and Developmental Disorders, 45(2), 548-559.
Hu, L. T., & Bentler, P. M. (1999). Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives. Structural Equation Modeling: A Multidisciplinary Journal, 6(1), 1-55.
Kerns, C. M., & Kendall, P. C. (2012). The presentation and classification of anxiety in autism spectrum disorder. Clinical Psychology: Science and Practice, 19(4), 323-347.
Kerns, C. M., Kendall, P. C., Berry, L., Souders, M. C., Franklin, M. E., Schultz, R. T., … Herrington, J. (2014). Traditional and atypical presentations of anxiety in youth with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44(11), 2851-2861.
Kerns, C. M., Renno, P., Kendall, P. C., Wood, J. J., & Storch, E. A. (2017). Anxiety disorders interview schedule - autism addendum: Reliability and validity in children with autism spectrum disorder. Journal of Clinical Child & Adolescent Psychology, 46(1), 88-100.
Kotov, R., Chang, S. W., Fochtmann, L. J., Mojtabai, R., Carlson, G. A., Sedler, M. J., & Bromet, E. J. (2010). Schizophrenia in the internalizing-externalizing framework: A third dimension? Schizophrenia Bulletin, 37(6), 1168-1178.
Kotov, R., Krueger, R. F., & Watson, D. (2018). A paradigm shift in psychiatric classification: The Hierarchical Taxonomy Of Psychopathology (HiTOP). World Psychiatry, 17(1), 24-25.
Kotov, R., Krueger, R. F., Watson, D., Achenbach, T. M., Althoff, R. R., Bagby, R. M., … Eaton, N. R. (2017). The hierarchical taxonomy of psychopathology (HiTOP): A dimensional alternative to traditional nosologies. Journal of Abnormal Psychology, 126(4), 454-477.
Kotov, R., Ruggero, C. J., Krueger, R. F., Watson, D., Yuan, Q., & Zimmerman, M. (2011). New dimensions in the quantitative classification of mental illness. Archives of General Psychiatry, 68(10), 1003-1011.
Kramer, M. D., Krueger, R. F., & Hicks, B. M. (2008). The role of internalizing and externalizing liability factors in accounting for gender differences in the prevalence of common psychopathological syndromes. Psychological Medicine, 38(01), 51-61.
Krueger, R. F. (2018). Empirical psychopathology classification and the importance of trans-diagnostic dimensional factors. Journal of the American Academy of Child & Adolescent Psychiatry, 57(6), 366-367.
Krueger, R. F., Caspi, A., Moffitt, T. E., & Silva, P. A. (1998). The structure and stability of common mental disorders (DSM-III-R): A longitudinal-epidemiological study. Journal of Abnormal Psychology, 107(2), 216-227.
Krueger, R. F., Chentsova-Dutton, Y. E., Markon, K. E., Goldberg, D. P., & Ormel, J. (2003). A cross-cultural study of the structure of comorbidity among common psychopathological syndromes in the general health care setting. Journal of Abnormal Psychology, 107, 216-227.
Krueger, R. F., & Markon, K. E. (2006). Reinterpreting comorbidity: A model-based approach to understanding and classifying psychopathology. Annual Review of Clinical Psychology, 2, 111-133.
Lecavalier, L., Gadow, K. D., DeVincent, C. J., & Edwards, M. C. (2009). Validation of DSM-IV model of psychiatric syndromes in children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(2), 278-289.
Lecavalier, L., Leone, S., & Wiltz, J. (2006). The impact of behaviour problems on caregiver stress in young people with autism spectrum disorder. Journal of Intellectual Disability Research, 50, 172-183.
Lecavalier, L., McCracken, C. E., Aman, M. G., McDougle, C. J., McCracken, J. T., Tierney, E., … Scahill, L. (2019). An exploration of concomitant psychiatric disorders in children with autism spectrum disorder. Comprehensive Psychiatry, 88, 57-64.
Lecavalier, L., Gadow, K. D., Devincent, C. J., Houts, C. R., & Edwards, M. C. (2011). Validity of DSM-IV syndromes in preschoolers with autism spectrum disorders. Autism, 15(5), 527-543.
Lerner, M. D., De Los Reyes, A., Drabick, D. A. G., Gerber, A. H., & Gadow, K. D. (2017). Informant discrepancy defines discrete, clinically-useful autism spectrum disorder subgroups. Journal of Child Psychology and Psychiatry, 58(7), 829-839.
Levy, S. E., Giarelli, E., Lee, L. C., Schieve, L. A., Kirby, R. S., Cunniff, C., … Rice, C. E. (2010). Autism spectrum disorder and co-occurring developmental, psychiatric, and medical conditions among children in multiple populations of the United States. Journal of Developmental & Behavioral Pediatrics, 31(4), 267-275.
Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., … Rutter, M. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205-223.
Mandell, D. S., Morales, K. H., Marcus, S. C., Stahmer, A. C., Doshi, J., & Polsky, D. E. (2008). Psychotropic medication use among medicaid-enrolled children with autism spectrum disorders. Pediatrics, 121(3), e441-e448.
Matson, J. L., & Williams, L. W. (2013). Differential diagnosis and comorbidity: Distinguishing autism from other mental health issues. Neuropsychiatry, 3(2), 233-243.
Mendelson, J. L., Gates, J. A., & Lerner, M. D. (2016). Friendship in school-age boys with autism spectrum disorders: A meta-analytic summary and developmental, process-based model. Psychological Bulletin, 142(6), 601.
Meredith, W. (1993). Measurement invariance, factor analysis and factorial invariance. Psychometrika, 58(4), 525-543.
Moskowitz, L. J., Rosen, T. E., Lerner, M. D., & Levine, K. (2016). Assessment of anxiety in youth with autism spectrum disorder. In C. Kerns, E. Storch, P. Kendall, J. J. Wood, & P. Renno (Eds.), Evidence based assessment and treatment of anxiety in children and adolescents with autism spectrum disorder. Elsevier.
Muthén, L., & Muthén, B. (2013). Mplus: Statistical analysis with latent variables. User's guide (Version 7.11). Los Angeles, CA: Muthén and Muthén.
Noordhof, A., Krueger, R. F., Ormel, J., Oldehinkel, A. J., & Hartman, C. A. (2015). Integrating autism-related symptoms into the dimensional internalizing and externalizing model of psychopathology. The TRAILS Study. Journal of Abnormal Child Psychology, 43(3), 577.
Ogilvie, J. M., Stewart, A. L., Chan, R. C. K., & Shum, D. H. (2011). Neuropsychological measures of executive function and antisocial behavior: A meta-analysis. Criminology, 49(4), 1063-1107.
Pachankis, J. E., Hatzenbuehler, M. L., Rendina, H. J., Safren, S. A., & Parsons, J. T. (2015). LGB-affirmative cognitive-behavioral therapy for young adult gay and bisexual men: A randomized controlled trial of a transdiagnostic minority stress approach. Journal of Consulting and Clinical Psychology, 83(5), 875-889.
Pellecchia, M., Connell, J. E., Kerns, C. M., Xie, M., Marcus, S. C., & Mandell, D. S. (2016). Child characteristics associated with outcome for children with autism in a school-based behavioral intervention. Autism, 20(3), 321-329.
Rodriguez-Seijas, C., Eaton, N. R., & Krueger, R. F. (2015). How transdiagnostic factors of personality and psychopathology can inform clinical assessment and intervention. Journal of Personality Assessment, 97(5), 425-435.
Rodriguez-Seijas, C., Eaton, N. R., & Pachankis, J. E. (2019). Prevalence of psychiatric disorders at the intersection of race and sexual orientation: Results from the National Epidemiologic Survey of Alcohol and Related Conditions-III. Journal of Consulting and Clinical Psychology, 87(4), 321-331.
Rommelse, N. N., Franke, B., Geurts, H. M., Hartman, C. A., & Buitelaar, J. K. (2010). Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder. European Child and Adolescent Psychiatry, 19, 281-295.
Rommelse, N. N., Geurts, H. M., Franke, B., Buitelaar, J. K., & Hartman, C. A. (2011). Review on cognitive and brain endophenotypes that may be common in autism spectrum disorder and attention-deficit/hyperactivity disorder and facilitate the search for pleiotropic genes. Neuroscience and Biobehavioral Reviews, 35, 1363-1396.
Rosen, T. E., Mazefsky, C. A., Vasa, R. A., & Lerner, M. D. (2018). Co-occurring psychiatric conditions in autism spectrum disorder. International Review of Psychiatry, 30, 40-61.
Russell, G., Mandy, W., Elliott, D., White, R., Pittwood, T., & Ford, T. (2019). Selection bias on intellectual ability in autism research: A cross-sectional review and meta-analysis. Molecular Autism, 10(1), 9.
Schendel, D. E., Overgaard, M., Christensen, J., Hjort, L., Jorgensen, M., Vestergaard, M., & Parner, E. T. (2016). Association of psychiatric and neurologic comorbidity with mortality among persons with autism spectrum disorder in a Danish population. JAMA Pediatrics, 170(3), 243-250.
Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child & Adolescent Psychiatry, 47(8), 921-929.
Steenkamp, J. B. E., & Baumgartner, H. (1998). Assessing measurement invariance in cross-national consumer research. Journal of Consumer Research, 25(1), 78-107.
Van Steensel, F. J., Bögels, S. M., & Perrin, S. (2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: A meta-analysis. Clinical Child and Family Psychology Review, 14(3), 302.
Waszczuk, M. A., Kotov, R., Ruggero, C., Gamez, W., & Watson, D. (2017). Hierarchical structure of emotional disorders: From individual symptoms to the spectrum. Journal of Abnormal Psychology, 126(5), 613-634.
Weber, R. J., & Gadow, K. D. (2017). Relation of psychiatric symptoms with epilepsy, asthma, and allergy in youth with ASD vs. psychiatry referrals. Journal of abnormal child psychology, 45(6), 1247-1257.
White, S. W., Mazefsky, C. A., Dichter, G. S., Chiu, P. H., Richey, J. A., & Ollendick, T. H. (2014). Social-cognitive, physiological, and neural mechanisms underlying emotion regulation impairments: Understanding anxiety in autism spectrum disorder. International Journal of Developmental Neuroscience, 39(C), 22-36. http://doi.org/10.1016/j.ijdevneu.2014.05.012
Willcutt, E. G., Doyle, A. E., Nigg, J. T., Faraone, S. V., & Pennington, B. F. (2005). Validity of the executive function theory of attention-deficit/hyperactivity disorder: A meta-analytic review. Biological Psychiatry, 57(11), 1336-1346.
Witwer, A., & Lecavalier, L. (2005). Treatment incidence and patterns in children and adolescents with autism spectrum disorders. Journal of Child and Adolescent Psychopharmacology, 15, 671-681.
Wood, J. J., & Gadow, K. D. (2010). Exploring the nature and function of anxiety in youth with autism spectrum disorders. Clinical Psychology: Science and Practice, 17, 281-292.