Fluorescence Imaging of Peripheral Nerves by a Na
Journal
Bioconjugate chemistry
ISSN: 1520-4812
Titre abrégé: Bioconjug Chem
Pays: United States
ID NLM: 9010319
Informations de publication
Date de publication:
20 11 2019
20 11 2019
Historique:
pubmed:
28
10
2019
medline:
23
9
2020
entrez:
25
10
2019
Statut:
ppublish
Résumé
Twenty million Americans suffer from peripheral nerve injury caused by trauma and medical disorders, resulting in a broad spectrum of potentially debilitating side effects. In one out of four cases, patients identify surgery as the root cause of their nerve injury. Particularly during tumor resections or after traumatic injuries, tissue distortion and poor visibility can challenge a surgeon's ability to precisely locate and preserve peripheral nerves. Intuitively, surgical outcomes would improve tremendously if nerves could be highlighted using an exogeneous contrast agent. In clinical practice, however, the current standard of care-visual examination and palpation-remains unchanged. To address this unmet clinical need, we explored the expression of voltage-gated sodium channel Na
Identifiants
pubmed: 31647222
doi: 10.1021/acs.bioconjchem.9b00612
pmc: PMC7372312
mid: NIHMS1608936
doi:
Substances chimiques
Cystine-Knot Miniproteins
0
NAV1.7 Voltage-Gated Sodium Channel
0
Peptide Fragments
0
SCN9A protein, human
0
Scn9a protein, mouse
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2879-2888Subventions
Organisme : NCI NIH HHS
ID : K99 CA218875
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA204441
Pays : United States
Organisme : NCI NIH HHS
ID : R43 CA228815
Pays : United States
Références
J Biol Chem. 2018 Jun 8;293(23):9041-9052
pubmed: 29703751
Cancer. 2011 Nov 1;117(21):4812-22
pubmed: 21484779
Cell Rep. 2018 Sep 18;24(12):3133-3145
pubmed: 30231997
ACS Chem Neurosci. 2014 Sep 17;5(9):749-51
pubmed: 25111714
Neurosurg Focus. 2015 Sep;39(3):E16
pubmed: 26323818
Eur Urol. 2010 Feb;57(2):179-92
pubmed: 19931974
Magn Reson Imaging. 2004 Jun;22(5):743-5
pubmed: 15172070
Nat Rev Cancer. 2013 Sep;13(9):653-62
pubmed: 23924645
Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1527-32
pubmed: 9037087
Urol Int. 2014;92(3):306-9
pubmed: 24334874
Ann Surg. 1998 Sep;228(3):320-30
pubmed: 9742915
J Am Acad Orthop Surg. 2000 Jul-Aug;8(4):243-52
pubmed: 10951113
Ann Surg. 1949 Oct;130(4):637-42
pubmed: 17859457
Phys Med Rehabil Clin N Am. 2016 Aug;27(3):687-715
pubmed: 27468673
Bioconjug Chem. 2010 Jul 21;21(7):1362-8
pubmed: 20583828
Mol Imaging. 2011 Apr;10(2):91-101
pubmed: 21439254
Clin Neurophysiol. 2008 Sep;119(9):1951-65
pubmed: 18482862
Dtsch Arztebl Int. 2014 Apr 18;111(16):273-9
pubmed: 24791754
J Biol Chem. 1997 Jun 6;272(23):14805-9
pubmed: 9169448
Biochim Biophys Acta Biomembr. 2017 May;1859(5):835-844
pubmed: 28115115
Pain. 1998 May;76(1-2):167-71
pubmed: 9696470
Craniomaxillofac Trauma Reconstr. 2015 Mar;8(1):1-13
pubmed: 25709748
Annu Rev Med. 2016;67:153-64
pubmed: 26768238
Biomed Res Int. 2014;2014:698256
pubmed: 25276813
Front Endocrinol (Lausanne). 2014 Jul 15;5:108
pubmed: 25076936
EMBO J. 1995 Mar 15;14(6):1084-90
pubmed: 7720699
Bioconjug Chem. 2014 Jan 15;25(1):171-7
pubmed: 24328216
Theranostics. 2017 Jan 7;7(3):573-593
pubmed: 28255352
Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12815-20
pubmed: 21768367
Ann Oncol. 1995 May;6(5):453-9
pubmed: 7669710
Eur Arch Otorhinolaryngol. 2015 Oct;272(10):3039-43
pubmed: 25248913
Nat Med. 2011 Sep 18;17(10):1315-9
pubmed: 21926976
J Urol. 2017 Feb;197(2S):S165-S170
pubmed: 28012765
Neurosurg Clin N Am. 2009 Jan;20(1):73-90, vii
pubmed: 19064181
Tech Doc Rep SAMTDR USAF Sch Aerosp Med. 1960 Sep;60-82:1-4
pubmed: 13729801
Ann Surg. 2019 Jul;270(1):69-76
pubmed: 30649014
Nat Biotechnol. 2011 Apr;29(4):352-6
pubmed: 21297616
Nature. 2006 Dec 14;444(7121):894-8
pubmed: 17167479
J Surg Oncol. 2011 Sep 1;104(3):323-32
pubmed: 21495033
Arch Surg. 2009 Feb;144(2):149-53; discussion 153
pubmed: 19221326