Investigation of human pancreatic cancer tissues by Fourier Transform Infrared Hyperspectral Imaging.
Fourier transform infrared hyperspectral imaging
multivariate analysis
pancreatic ductal adenocarcinoma
pancreatic neuroendocrine tumors
spectral biomarkers
Journal
Journal of biophotonics
ISSN: 1864-0648
Titre abrégé: J Biophotonics
Pays: Germany
ID NLM: 101318567
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
02
08
2019
revised:
24
09
2019
accepted:
16
10
2019
pubmed:
28
10
2019
medline:
24
6
2021
entrez:
25
10
2019
Statut:
ppublish
Résumé
Fourier-transform infrared hyperspectral imaging (FTIR-HSI) provides hyperspectral images containing both morphological and chemical information. It is widely applied in the biomedical field to detect tumor lesions, even at the early stage, by identifying specific spectral biomarkers. Pancreatic neoplasms present different prognoses and are not always easily classified by conventional analyses. In this study, tissue samples with diagnosis of pancreatic ductal adenocarcinoma and pancreatic neuroendocrine tumor were analyzed by FTIR-HSI and the spectral data compared with those from healthy and dysplastic samples. Multivariate/univariate approaches were complemented to hyperspectral images, and definite spectral markers of the different lesions identified. The malignant lesions were recognizable both from healthy/dysplastic pancreatic tissues (high values of phospholipids and triglycerides with shorter, more branched and less unsaturated alkyl chains) and between each other (different amounts of total lipids, phosphates and carbohydrates). These findings highlight different metabolic pathways characterizing the different samples, well detectable by FTIR-HSI.
Identifiants
pubmed: 31648419
doi: 10.1002/jbio.201960071
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e201960071Informations de copyright
© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Références
American Cancer Society, Cancer facts & figures 2019, https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/cancer-facts-figures-2019.html.
T. P. Yeo, R. H. Hruban, S. D. Leach, R. E. Wilentz, T. A. Sohn, S. E. Kern, C. A. Iacobuzio-Donahue, A. Maitra, M. Goggins, M. I. Canto, R. A. Abrams, D. Laheru, E. M. Jaffee, M. Hidalgo, C. J. Yeo, Curr. Probl. Cancer 2002, 26, 176.
W. R. Lloyd, R. H. Wilson, S. Y. Lee, M. Chandra, B. McKenna, D. Simeone, J. Scheiman, M.-A. Mycek, Biomed. Opt. Express 2014, 5, 9.
A. S. Takhar, P. Palaniappan, R. Dhingsa, D. N. Lobo, BMJ 2004, 329, 668.
G. Low, A. Panu, N. Millo, E. Leen, Radiographics 2011, 31, 993.
G. Klöppel, M. Anlauf, Pathol. Case Rev. 2006, 11, 256.
H. Sreedhar, V. K. Varma, P. L. Nguyen, B. Davidson, S. Akkina, G. Guzman, S. Setty, A. Kajdacsy-Balla, M. J. Walsh, J. Vis. Exp. 2015, 95, 1.
E. Giorgini, S. Sabbatini, C. Conti, C. Rubini, R. Rocchetti, M. Re, L. Vaccari, E. Mitri, V. Librando, J. Biomed. Opt. 2015, 20, 125003.
E. Giorgini, G. Tosi, C. Conti, S. Staibano, G. Ilardi, S. Sabbatini, Acta Part A Mol. Biomol. Spectrosc. 2015, 141, 99.
M. Z. Kastyak-Ibrahim, M. J. Nasse, M. Rak, C. Hirschmugl, M. R. Del Bigio, B. C. Albensi, K. M. Gough, NeuroImage 2012, 60, 376.
A. Kallenbach-Thieltges, F. Großerüschkamp, A. Mosig, M. Diem, A. Tannapfel, K. Gerwert, J. Biophotonics 2013, 6, 88.
M. J. Baker, E. Gazi, J. H. Shanks, P. Gardner, N. W. Clarke, M. D. Brown, J. H. Shanks, P. Gardner, N. W. Clarke, Br. J. Cancer 2008, 99, 1859.
G. E. Menzies, H. R. Fox, C. Marnane, L. Pope, V. Prabhu, S. Winter, A. V. Derrick, P. D. Lewis, Transl. Res. 2014, 163, 19.
K. Badizadegan, V. Backman, C. W. Boone, C. P. Crum, R. R. Dasari, I. Georgakoudi, K. Keefe, K. Munger, S. M. Shapshay, E. E. Sheetse, M. S. Feld, Faraday Discuss. 2004, 126, 265.
B. R. Wood, M. Kiupel, D. McNaughton, Vet. Pathol. 2014, 51, 224.
Y. Jusman, N. A. Mat Isa, S.-C. Ng, K. Hasikin, N. A. Abu Osman, J. Biomed. Opt. 2016, 21, 075005.
F. Elmi, A. F. Movaghar, M. M. Elmi, H. Alinezhad, N. Nikbakhsh, Acta Part A Mol. Biomol. Spectrosc. 2017, 187, 87.
J. Backhaus, R. Mueller, N. Formanski, N. Szlama, H.-G. Meerpohl, M. Eidt, P. Bugert, Vib. Spectrosc. 2010, 52, 173.
S. Gurunathan, M. Qasim, C. Park, H. Yoo, J.-H. Kim, K. Hong, Int. J. Mol. Sci. 2018, 19, 2269.
E. Kaznowska, J. Depciuch, K. Szmuc, J. Cebulski, J. Pharm. Biomed. Anal. 2017, 134, 259.
E. Kaznowska, K. Łach, J. Depciuch, R. Chaber, A. Koziorowska, S. Slobodian, K. Kiper, A. Chlebus, J. Cebulski, Infrared Phys. Technol. 2018, 89, 282.
J. Depciuch, A. Stanek-Widera, D. Lange, M. Biskup-Frużyńska, J. Stanek-Tarkowska, W. Czarny, J. Cebulski, Acta Part A Mol. Biomol. Spectrosc. 2018, 204, 18.
D. Sebiskveradze, B. Bertino, V. Gaydou, A.-S. Dugaret, M. Roquet, D. E. Zugaj, J. J. Voegel, P. Jeannesson, M. Manfait, O. Piot, J. Biophotonics 2018, 11, e201700380.
C. Morais, K. Lima, J. Braz. Chem. Soc. 2017, 29, 472.
C. L. M. Morais, R. F. Shore, M. G. Pereira, F. L. Martin, ACS Omega 2018, 3, 13399.
C. Petibois, G. Déléris, Trends Biotechnol. 2006, 24, 455.
A. N. A. Aryee, F. R. van de Voort, B. K. Simpson, Process Biochem. 2009, 44, 401.
B. Vileno, S. Jeney, A. Sienkiewicz, P. R. Marcoux, L. M. Miller, L. Forró, Biophys. Chem. 2010, 152, 164.
A. C. S. Talari, M. A. G. Martinez, Z. Movasaghi, S. Rehman, I. U. Rehman, Appl. Spectrosc. Rev. 2017, 52, 456.
K. Belbachir, R. Noreen, G. Gouspillou, C. Petibois, Anal. Bioanal. Chem. 2009, 395, 829.
P. Zucchiatti, E. Mitri, S. Kenig, F. Billè, G. Kourousias, D. E. Bedolla, L. Vaccari, Anal. Chem. 2016, 88, 12090.
M. Weniger, K. C. Honselmann, A. S. Liss, Cancers (Basel). 2018, 10, 316.
P. T. Wong, R. K. Wong, T. A. Caputo, T. A. Godwin, B. Rigas, Proc. Natl. Acad. Sci. U. S. A. 1991, 88, 10988.
S. Caine, P. Heraud, M. J. Tobin, D. McNaughton, C. C. A. Bernard, NeuroImage 2012, 59, 3624.
J. Kneipp, M. Beekes, P. Lasch, D. Naumann, J. Neurosci. 2002, 22, 2989.
D. Simonova, I. Karamancheva, Biotechnol. Biotechnol. Equip. 2013, 27, 4200.
C. R. Santos, A. Schulze, FEBS J. 2012, 279, 2610.
Y.-J. Chen, Y.-D. Cheng, H.-Y. Liu, P.-Y. Lin, C.-S. Wang, Chang Gung Med. J. 2006, 29, 518.
M. Khanmohammadi, A. B. Garmarudi, TrAC Trends Anal. Chem. 2011, 30, 864.
T. Hata, K. Kawamoto, H. Eguchi, Y. Kamada, S. Takamatsu, T. Maekawa, S. Nagaoka, D. Yamada, Y. Iwagami, T. Asaoka, T. Noda, H. Wada, K. Gotoh, A. Masamune, E. Miyoshi, M. Mori, Y. Doki, Pancreas 2017, 46, 1259.
P. Capelli, G. Martignoni, F. Pedica, M. Falconi, D. Antonello, G. Malpeli, A. Scarpa, Arch. Pathol. Lab. Med. 2009, 133, 350.