Usefulness of video thermography in the evaluation of platelet-rich plasma effectiveness in vulvar lichen sclerosus: preliminary study.


Journal

The Journal of dermatological treatment
ISSN: 1471-1753
Titre abrégé: J Dermatolog Treat
Pays: England
ID NLM: 8918133

Informations de publication

Date de publication:
Aug 2021
Historique:
pubmed: 28 10 2019
medline: 13 7 2021
entrez: 26 10 2019
Statut: ppublish

Résumé

Lichen sclerosus (LS) is a chronic-relapsing and potentially serious skin disease that has a preference for genital skin. Currently, there is no standardized method for assessing the effects of therapies. The objective of this preliminary study is to use video thermography (VTG) in the evaluation of vulvar lichen sclerosus (VLS) before and after platelet-rich plasma (PRP) therapy. A sample of six female patients was enrolled. Patients were subjected to PRP treatment. Patients selected for the study had been assessed at baseline (T0) and after 7 and 30 d from PRP treatment (T1 and T2, respectively). Clinical and VTG evaluation was executed in every visit. The VTG examination showed at least one hypothermic area (HA) in all our patients. The average temperature measured in the vulvar and perineal region taken as a reference for each patient was found to be between 33.7 °C and 36.3 °C, with a fair difference between the patients. HAs showed thermal differences which varied between 2.2 °C and 1.2 °C. It is demonstrated here that PRP offers satisfactory effectiveness in treating VLS and that video thermograpy could represent a useful paraclinic method in the identification and follow-up of LS.

Sections du résumé

BACKGROUND BACKGROUND
Lichen sclerosus (LS) is a chronic-relapsing and potentially serious skin disease that has a preference for genital skin. Currently, there is no standardized method for assessing the effects of therapies.
OBJECTIVE OBJECTIVE
The objective of this preliminary study is to use video thermography (VTG) in the evaluation of vulvar lichen sclerosus (VLS) before and after platelet-rich plasma (PRP) therapy.
METHODS METHODS
A sample of six female patients was enrolled. Patients were subjected to PRP treatment. Patients selected for the study had been assessed at baseline (T0) and after 7 and 30 d from PRP treatment (T1 and T2, respectively). Clinical and VTG evaluation was executed in every visit.
RESULTS RESULTS
The VTG examination showed at least one hypothermic area (HA) in all our patients. The average temperature measured in the vulvar and perineal region taken as a reference for each patient was found to be between 33.7 °C and 36.3 °C, with a fair difference between the patients. HAs showed thermal differences which varied between 2.2 °C and 1.2 °C.
CONCLUSIONS CONCLUSIONS
It is demonstrated here that PRP offers satisfactory effectiveness in treating VLS and that video thermograpy could represent a useful paraclinic method in the identification and follow-up of LS.

Identifiants

pubmed: 31648588
doi: 10.1080/09546634.2019.1685644
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

568-571

Auteurs

M Tedesco (M)

Department of Plastic and Reconstructive Surgery, San Gallicano Dermatological Institute, IRCCS, Rome, Italy.

V Garelli (V)

Department of Plastic and Reconstructive Surgery, San Gallicano Dermatological Institute, IRCCS, Rome, Italy.

F Elia (F)

Radiology and Diagnostic Imaging Unit, San Gallicano Dermatological Institute, IRCCS, Rome, Italy.

G Chicherchia (G)

Musculo-Skeletal Tissue Bank, Rome, Italy.

M L Foddai (ML)

Immunohaematology and Trasfusion Medicine, Regina Elena National Cancer Institute, Rome, Italy.

A Latini (A)

Infective Dermatologic Department, San Gallicano Dermatological Institute, IRCCS, Rome, Italy.

A Morrone (A)

Scientific Director San Gallicano Dermatological Institute, IRCCS, Rome, Italy.

E Migliano (E)

Department of Plastic and Reconstructive Surgery, San Gallicano Dermatological Institute, IRCCS, Rome, Italy.

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Classifications MeSH