Crosstalk Between Signaling Pathways Involved in the Regulation of Airway Smooth Muscle Cell Hyperplasia.
airway remodeling
ASM cell apoptosis
ASM cell migration
ASM cell proliferation
ASM hyperplasia
Journal
Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923
Informations de publication
Date de publication:
2019
2019
Historique:
received:
25
06
2019
accepted:
06
09
2019
entrez:
26
10
2019
pubmed:
28
10
2019
medline:
28
10
2019
Statut:
epublish
Résumé
Increased ASM mass, primarily due to ASM hyperplasia, has been recognized as a hallmark of airway remodeling in asthma. Increased ASM mass is the major contributor to the airway narrowing, thus worsening the bronchoconstriction in response to stimuli. Inflammatory mediators and growth factors released during inflammation induce increased ASM mass surrounding airway wall
Identifiants
pubmed: 31649532
doi: 10.3389/fphar.2019.01148
pmc: PMC6794426
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1148Informations de copyright
Copyright © 2019 Yap, Israf, Harith, Tham and Sulaiman.
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