Telomere length tracking in children and their parents: implications for adult onset diseases.
aging
leukocytes
telomere attrition
terminal restriction fragments
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
pubmed:
28
10
2019
medline:
9
6
2020
entrez:
26
10
2019
Statut:
ppublish
Résumé
Adults with comparatively short or long leukocyte telomere length (LTL) typically continue to display comparatively short or long LTL throughout life. This LTL tracking stems from the inability of person-to-person variation in age-dependent LTL shortening during adulthood to offset the wide interindividual LTL variation established prior to adult life. However, LTL tracking in children is unstudied. This study aimed to examine LTL shortening rates and tracking in children and their parents. Longitudinal study in children (
Identifiants
pubmed: 31652401
doi: 10.1096/fj.201901275R
pmc: PMC6894096
doi:
Banques de données
ClinicalTrials.gov
['NCT01391442']
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
14248-14253Références
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