Impact of Fenugreek on Milk Production in Rodent Models of Lactation Challenge.
fenugreek
litter size
maternal protein restriction
milk composition
milk flow
plasma metabolic parameters
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
24 Oct 2019
24 Oct 2019
Historique:
received:
30
09
2019
revised:
18
10
2019
accepted:
21
10
2019
entrez:
27
10
2019
pubmed:
28
10
2019
medline:
9
4
2020
Statut:
epublish
Résumé
Fenugreek, a herbal remedy, has long been used as galactologue to help mothers likely to stop breastfeeding because of perceived insufficient milk production. However, few studies highlight the efficacy of fenugreek in enhancing milk production. The aims of our study were to determine whether fenugreek increased milk yield in rodent models of lactation challenge and if so, to verify the lack of adverse effects on dam and offspring metabolism. Two lactation challenges were tested: increased litter size to 12 pups in dams fed a 20% protein diet and perinatal restriction to an 8% protein diet with eight pups' litter, with or without 1 g.kg
Identifiants
pubmed: 31653107
pii: nu11112571
doi: 10.3390/nu11112571
pmc: PMC6893785
pii:
doi:
Substances chimiques
Alkaloids
0
Biomarkers
0
Fatty Acids
0
Milk Proteins
0
trigonelline
3NQ9N60I00
Lactose
J2B2A4N98G
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Laboratoire France Bébé Nutrition
ID : Cifre grant 2017.0004
Déclaration de conflit d'intérêts
Thomas Sevrin is employed by France Bébé Nutrition, which funded this study.
Références
FEBS Lett. 1980 Aug 25;117 Suppl:K93-105
pubmed: 6998730
Rev Tuberc Pneumol (Paris). 1966 Dec;30(12):41-5
pubmed: 6011133
Pediatrics. 2012 Mar;129(3):e827-41
pubmed: 22371471
J Obstet Gynecol Neonatal Nurs. 2009 May-Jun;38(3):259-68
pubmed: 19538614
J Nutr. 1993 Nov;123(11):1939-51
pubmed: 8229312
PLoS One. 2017 Jul 17;12(7):e0180550
pubmed: 28715436
Comp Biochem Physiol A Comp Physiol. 1991;98(3-4):535-42
pubmed: 1674460
J Lipid Res. 1998 Nov;39(11):2237-49
pubmed: 9799810
Ann Pharmacother. 2012 Oct;46(10):1392-404
pubmed: 23012383
Fundam Clin Pharmacol. 2013 Jun;27(3):279-87
pubmed: 22172053
J Pediatr. 2017 Feb;181:294-297.e3
pubmed: 27871690
J Evid Based Complementary Altern Med. 2016 Jan;21(1):53-62
pubmed: 25922446
Early Hum Dev. 1984 Sep;10(1-2):115-22
pubmed: 6389080
Biochem J. 1984 Jun 1;220(2):455-60
pubmed: 6146315
Physiol Behav. 2008 Mar 18;93(4-5):826-34
pubmed: 18187167
Am J Physiol. 1988 Nov;255(5 Pt 2):F953-6
pubmed: 3189565
Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E582-6
pubmed: 16608884
Trends Endocrinol Metab. 2012 Sep;23(9):420-8
pubmed: 22819213
Breastfeed Med. 2017 Sep;12(7):401-409
pubmed: 28714737
Biochim Biophys Acta. 1977 May 25;487(2):297-306
pubmed: 861238
Lancet. 2016 Jan 30;387(10017):475-90
pubmed: 26869575
Acta Physiol Scand. 1987 Nov;131(3):391-6
pubmed: 3321913
Cancer Causes Control. 2007 Jun;18(5):517-23
pubmed: 17450440
Acta Physiol (Oxf). 2014 Jan;210(1):188-201
pubmed: 24010762
Am J Physiol. 1991 Jun;260(6 Pt 2):R1104-13
pubmed: 2058738
ISRN Obstet Gynecol. 2011;2011:876502
pubmed: 21637364
Matern Child Health J. 2013 May;17(4):714-22
pubmed: 22729659
JAMA Intern Med. 2018 Mar 1;178(3):328-337
pubmed: 29340577
Diabetes Care. 2013 May;36(5):1229-35
pubmed: 23275353
J Anim Sci. 1998 Dec;76(12):3072-8
pubmed: 9928612
Pharmacol Res. 1999 Nov;40(5):405-9
pubmed: 10527654
J Nurs Scholarsh. 2008;40(4):355-63
pubmed: 19094151
Obes Facts. 2019;12(2):226-243
pubmed: 31030194
Biogerontology. 2014 Apr;15(2):177-98
pubmed: 24337988
Pediatr Res. 2008 Apr;63(4):358-63
pubmed: 18356739
J Nutr Biochem. 2015 Jul;26(7):784-95
pubmed: 25935308
Lab Anim. 1975 Jan;9(1):43-7
pubmed: 1117695