Possible Empirical Evidence of Glymphatic System on Computed Tomography After Endovascular Perforations.
Endovascular
Extravasation
Glymphatic
Stroke
Subarachnoid hemorrhage
Journal
World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
received:
26
08
2019
revised:
13
10
2019
accepted:
14
10
2019
pubmed:
28
10
2019
medline:
7
3
2020
entrez:
27
10
2019
Statut:
ppublish
Résumé
The glial-lymphatic pathway is a fluid-clearance pathway consisting of a para-arterial route for the flow of cerebrospinal fluid along perivascular spaces and subsequently toward the brain interstitium. In this case series, we aim to investigate an empirical demonstration of glymphatic clearance of extravasated iodine following perforation incurred during endovascular therapy on serial computed tomography. Six consecutive cases of endovascular perforation during thrombectomy performed between 2005 and 2018 were retrospectively collected by searching our internal database of total 446 thrombectomies. Two cases were excluded because care was withdrawn shortly following the procedure and no follow-up imaging was available. One case was excluded because a ventricular drain was placed. Three cases were hence included in this analysis. All 3 cases demonstrated progressive absorption of contrast by the brain parenchyma with eventual contrast disappearance. We described a likely in vivo computed tomography correlate of the glymphatic system in a cohort of patients who sustained intraprocedural extravasation during thrombectomy for acute ischemic stroke.
Sections du résumé
BACKGROUND
BACKGROUND
The glial-lymphatic pathway is a fluid-clearance pathway consisting of a para-arterial route for the flow of cerebrospinal fluid along perivascular spaces and subsequently toward the brain interstitium. In this case series, we aim to investigate an empirical demonstration of glymphatic clearance of extravasated iodine following perforation incurred during endovascular therapy on serial computed tomography.
METHODS
METHODS
Six consecutive cases of endovascular perforation during thrombectomy performed between 2005 and 2018 were retrospectively collected by searching our internal database of total 446 thrombectomies. Two cases were excluded because care was withdrawn shortly following the procedure and no follow-up imaging was available. One case was excluded because a ventricular drain was placed. Three cases were hence included in this analysis.
RESULTS
RESULTS
All 3 cases demonstrated progressive absorption of contrast by the brain parenchyma with eventual contrast disappearance.
CONCLUSIONS
CONCLUSIONS
We described a likely in vivo computed tomography correlate of the glymphatic system in a cohort of patients who sustained intraprocedural extravasation during thrombectomy for acute ischemic stroke.
Identifiants
pubmed: 31655242
pii: S1878-8750(19)32708-1
doi: 10.1016/j.wneu.2019.10.089
pii:
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e400-e404Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.