True single-port cholecystectomy with ICG cholangiography through a single 15-mm trocar using the new surgical platform "symphonX": first human case study with a commercially available device.


Journal

Surgical endoscopy
ISSN: 1432-2218
Titre abrégé: Surg Endosc
Pays: Germany
ID NLM: 8806653

Informations de publication

Date de publication:
06 2020
Historique:
received: 25 07 2019
accepted: 15 10 2019
pubmed: 30 10 2019
medline: 12 5 2021
entrez: 30 10 2019
Statut: ppublish

Résumé

Minimally invasive single-port surgery is often associated with large incisions up to 2-3 cm, complicated handling due to the lack of triangulation, and instrument crossing. Aim of this prospective study was to perform true single-port surgery (cholecystectomy) without the use of assisting trocars using a new surgical platform that allows for triangulation incorporating robotic features, and to measure the perioperative outcome and cosmetic results. As the first European site after FDA and CE-mark approval, the new device has been introduced to our academic center. In patients with cholecystitis and cholecystolithiasis, the operation was performed through only one 15-mm trocar. For patients safety, intraoperative cholangiography using intravenous ICG and a standard Stryker 1588 system was routinely performed. Symphonx was used in n = 12 patients for abdominal surgery (6 females, mean age 42.5 [30-77], mean BMI 26.2 [19.3-38.9]. A total of 8 patients underwent surgery using no additional ports besides the 15-mm trocar; in the remaining patients, one assisting instrument (3-5 mm) was used. Mean OR time was 107 [72-221] minutes. The postoperative course was uneventful in 11 patients; in one patient, a seroma at the surgical site required interventional drainage 1 month postoperatively. No intraoperative complications occurred. This is the first human case series using the commercially available symphonX platform for abdominal laparoscopic surgery and the first series using the system without assisting instruments. Laparoscopic cholecystectomy in patients with cholecystitis and cholecystolithiasis using the symphonX platform through only one 15-mm trocar is feasible, safe, and more cost-efficient compared to robotic platforms.

Sections du résumé

BACKGROUND
Minimally invasive single-port surgery is often associated with large incisions up to 2-3 cm, complicated handling due to the lack of triangulation, and instrument crossing. Aim of this prospective study was to perform true single-port surgery (cholecystectomy) without the use of assisting trocars using a new surgical platform that allows for triangulation incorporating robotic features, and to measure the perioperative outcome and cosmetic results.
METHODS
As the first European site after FDA and CE-mark approval, the new device has been introduced to our academic center. In patients with cholecystitis and cholecystolithiasis, the operation was performed through only one 15-mm trocar. For patients safety, intraoperative cholangiography using intravenous ICG and a standard Stryker 1588 system was routinely performed.
RESULTS
Symphonx was used in n = 12 patients for abdominal surgery (6 females, mean age 42.5 [30-77], mean BMI 26.2 [19.3-38.9]. A total of 8 patients underwent surgery using no additional ports besides the 15-mm trocar; in the remaining patients, one assisting instrument (3-5 mm) was used. Mean OR time was 107 [72-221] minutes. The postoperative course was uneventful in 11 patients; in one patient, a seroma at the surgical site required interventional drainage 1 month postoperatively. No intraoperative complications occurred.
CONCLUSION
This is the first human case series using the commercially available symphonX platform for abdominal laparoscopic surgery and the first series using the system without assisting instruments. Laparoscopic cholecystectomy in patients with cholecystitis and cholecystolithiasis using the symphonX platform through only one 15-mm trocar is feasible, safe, and more cost-efficient compared to robotic platforms.

Identifiants

pubmed: 31659506
doi: 10.1007/s00464-019-07229-4
pii: 10.1007/s00464-019-07229-4
doi:

Types de publication

Evaluation Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2722-2729

Références

Reynolds W Jr (2001) The first laparoscopic cholecystectomy. JSLS 5(1):89–94
pubmed: 11304004 pmcid: 3015420
Mühe E (1992) Long-term follow-up after laparoscopic cholecystectomy. Endoscopy 24(9):754–758
pubmed: 1468391 doi: 10.1055/s-2007-1009119
Keus F, de Jong JA, Gooszen HG, van Laarhoven CJ (2006) Laparoscopic versus small-incision cholecystectomy for patients with symptomatic cholecystolithiasis. Cochrane Database Syst Rev 8(4):CD006229 Review
Berducci M, Fuchs HF, Omelanczuk P, Broderick RC, Harnsberger CR, Langert J, Nefa J, Jaureguiberry P, Gomez P, Miranda L, Jacobsen GR, Sandler BJ, Horgan S (2016) Phase II clinical experience and long-term follow-up using the next-generation single-incision platform FMX314. Surg Endosc 30(3):953–960
pubmed: 26123331 doi: 10.1007/s00464-015-4319-2
Allemann P, Demartines N, Schäfer M (2014) Remains of the day: biliary complications related to single-port laparoscopic cholecystectomy. World J Gastroenterol 20(3):843–851
pubmed: 24574757 pmcid: 3921493 doi: 10.3748/wjg.v20.i3.843
Tranchart H, Ketoff S, Lainas P, Pourcher G, Di Giuro G, Tzanis D, Ferretti S, Dautruche A, Devaquet N, Dagher I (2003) Single incision laparoscopic cholecystectomy: for what benefit? HPB (Oxford) 15(6):433–438
doi: 10.1111/j.1477-2574.2012.00612.x
Gonzalez AM, Rabaza JR, Donkor C, Romero RJ, Kosanovic R, Verdeja JC (2013) Single-incision cholecystectomy: a comparative study of standard laparoscopic, robotic, and SPIDER platforms. Surg Endosc 27(12):4524–4531
pubmed: 23943118 doi: 10.1007/s00464-013-3105-2
Haber GP, Autorino R, Laydner H, Yang B, White MA, Hillyer S, Altunrende F, Khanna R, Spana G, Wahib I, Fareed K, Stein RJ, Kaouk JH (2012) SPIDER surgical system for urologic procedures with laparoendoscopic single-site surgery: from initial laboratory experience to first clinical application. Eur Urol 61(2):415–422
pubmed: 21216523 doi: 10.1016/j.eururo.2010.12.033
Broderick RC, Omelanczuk P, Harnsberger CR, Fuchs HF, Berducci M, Nefa J, Nicolia J, Almadani M, Jacobsen GR, Sandler BJ, Horgan S (2015) Laparoscopic cholecystectomy using a novel single-incision surgical platform through a standard 15 mm trocar: initial experience and technical details. Surg Endosc 29(5):1250–1256
pubmed: 25149635 doi: 10.1007/s00464-014-3779-0
Marks JM, Phillips MS, Tacchino R, Roberts K, Onders R, DeNoto G, Gecelter G, Rubach E, Rivas H, Islam A, Soper N, Paraskeva P, Rosemurgy A, Ross S, Shah S (2013) Single-incision laparoscopic cholecystectomy is associated with improved cosmesis scoring at the cost of significantly higher hernia rates: 1-year results of a prospective randomized, multicenter, single-blinded trial of traditional multiport laparoscopic cholecystectomy vs single-incision laparoscopic cholecystectomy. J Am Coll Surg 216(6):1037–1047 discussion 1047-8
pubmed: 23619321 doi: 10.1016/j.jamcollsurg.2013.02.024
Haueter R, Schütz T, Raptis DA, Clavien PA, Zuber M (2017) Meta-analysis of single-port versus conventional laparoscopic cholecystectomy comparing body image and cosmesis. Br J Surg 104(9):1141–1159
pubmed: 28569406 doi: 10.1002/bjs.10574
Chen KH, Chen LR, Seow KM (2015) Ovarian suspension with adjustable sutures: an easy and helpful technique for facilitating laparoendoscopic single-site gynecologic surgery. J Minim Invasive Gynecol 22(5):767–775
pubmed: 25757814 doi: 10.1016/j.jmig.2015.02.018
Karavani G, Schachter-Safrai N, Chill HH, Mordechai Daniel T, Bauman D, Revel A (2018) Single-incision laparoscopic surgery for ovarian tissue cryopreservation. J Minim Invasive Gynecol 25(3):474–479
pubmed: 29032255 doi: 10.1016/j.jmig.2017.10.007
Liu X, Li JB, Shi G, Guo R, Zhang R (2018) Systematic review of single-incision versus conventional multiport laparoscopic surgery for sigmoid colon and rectal cancer. World J Surg Oncol 16(1):220
pubmed: 30414613 pmcid: 6230377 doi: 10.1186/s12957-018-1521-4
Jaschinski T, Mosch CG, Eikermann M, Neugebauer EA, Sauerland S (2018) Laparoscopic versus open surgery for suspected appendicitis. Cochrane Database Syst Rev 11:1–2
Romanelli JR, Earle DB (2009) Single-port laparoscopic surgery: an overview. Surg Endosc 23(7):1419–1427
pubmed: 19347400 doi: 10.1007/s00464-009-0463-x
Wagner MJ, Kern H, Hapfelmeier A, Mehler J, Schoenberg MH (2013) Single-port cholecystectomy versus multi-port cholecystectomy: a prospective cohort study with 222 patients. World J Surg 37(5):991–998
pubmed: 23435700 doi: 10.1007/s00268-013-1946-4
Evers L, Bouvy N, Branje D, Peeters A (2017) Single-incision laparoscopic cholecystectomy versus conventional four-port laparoscopic cholecystectomy: a systematic review and meta-analysis. Surg Endosc 31(9):3437–3448
pubmed: 28039641 doi: 10.1007/s00464-016-5381-0
Arezzo A, Passera R, Forcignanò E, Rapetti L, Cirocchi R, Morino M (2018) Single-incision laparoscopic cholecystectomy is responsible for increased adverse events: results of a meta-analysis of randomized controlled trials. Surg Endosc 32(9):3739–3753
doi: 10.1007/s00464-018-6143-y pubmed: 29523982
Antoniou SA, García-Alamino JM, Hajibandeh S, Hajibandeh S, Weitzendorfer M, Muysoms FE, Granderath FA, Chalkiadakis GE, Emmanuel K, Antoniou GA, Gioumidou M, Iliopoulou-Kosmadaki S, Mathioudaki M, Souliotis K (2018) Single-incision surgery trocar-site hernia: an updated systematic review meta-analysis with trial sequential analysis by the Minimally Invasive Surgery Synthesis of Interventions Outcomes Network (MISSION). Surg Endosc 32(1):14–23
pubmed: 28726142 doi: 10.1007/s00464-017-5717-4
Lee Y, Roh Y, Kim M, Kim Y, Kim K, Kang S, Jang E (2018) Analysis of post-operative complication in single-port laparoscopic cholecystectomy: a retrospective analysis in 817 cases from a surgeon. J Minim Access Surg 14(4):311–315
pubmed: 29319016 pmcid: 6130182 doi: 10.4103/jmas.JMAS_168_17
Olweny EO, Mir SA, Best SL, Park SK, Donnally Iii C, Cadeddu JA, Tracy CR (2012) Importance of cosmesis to patients undergoing renal surgery: a comparison of laparoendoscopic single-site (LESS), laparoscopic and open surgery. BJU Int 110(2):268–272
pubmed: 22177193 doi: 10.1111/j.1464-410X.2011.10784.x
Lurje G, Raptis DA, Steinemann DC, Amygdalos I, Kambakamba P, Petrowsky H, Lesurtel M, Zehnder A, Wyss R, Clavien PA, Breitenstein S (2015) Cosmesis and body image in patients undergoing single-port versus conventional laparoscopic cholecystectomy: a multicenter double-blinded randomized controlled trial (SPOCC-trial). Ann Surg 262(5):728–734
pubmed: 26583659 doi: 10.1097/SLA.0000000000001474
Escobar PF, Haber GP, Kaouk J, Kroh M, Chalikonda S, Falcone T (2011) Single-port surgery: laboratory experience with the daVinci single-site platform. JSLS 15(2):136–141
pubmed: 21902962 pmcid: 3148858 doi: 10.4293/108680811X13022985132128
Kroh M, El-Hayek K, Rosenblatt S, Chand B, Escobar P, Kaouk J, Chalikonda S (2011) First human surgery with a novel single-port robotic system: cholecystectomy using the da Vinci Single-Site platform. Surg Endosc 25(11):3566–3573
pubmed: 21638179 doi: 10.1007/s00464-011-1759-1
Pietrabissa A, Sbrana F, Morelli L, Badessi F, Pugliese L, Vinci A, Klersy C, Spinoglio G (2012) Overcoming the challenges of single-incision cholecystectomy with robotic single-site technology. Arch Surg 147(8):709–714
pubmed: 22508669 doi: 10.1001/archsurg.2012.508
Morel P, Buchs NC, Iranmanesh P, Pugin F, Buehler L, Azagury DE, Jung M, Volonte F, Hagen ME (2014) Robotic single-site cholecystectomy. J Hepatobiliary Pancreat Sci 21(1):18–25
pubmed: 24142898 doi: 10.1002/jhbp.36
Chang SK, Wang YL, Shen L, Iyer SG, Madhavan K (2015) A randomized controlled trial comparing post-operative pain in single-incision laparoscopic cholecystectomy versus conventional laparoscopic cholecystectomy. World J Surg 39(4):897–904
pubmed: 25446490 doi: 10.1007/s00268-014-2903-6
van den Boezem PB, Velthuis S, Lourens HJ, Cuesta MA, Sietses C (2014) Single-incision and NOTES cholecystectomy, are there clinical or cosmetic advantages when compared to conventional laparoscopic cholecystectomy? A case-control study comparing single-incision, transvaginal, and conventional laparoscopic technique for cholecystectomy. World J Surg 38(1):25–32
pubmed: 24081531 doi: 10.1007/s00268-013-2221-4
Cheng H, Chen BP, Soleas IM, Ferko NC, Cameron CG, Hinoul P (2017) Prolonged operative duration increases risk of surgical site infections: a systematic review. Surg Infect (Larchmt) 18(6):722–735
doi: 10.1089/sur.2017.089
Catanzarite T, Saha S, Pilecki MA, Kim JY, Milad MP (2015) Longer operative time during benign laparoscopic and robotic hysterectomy is associated with increased 30-day perioperative complications. J Minim Invasive Gynecol 22(6):1049–1058
pubmed: 26070725 doi: 10.1016/j.jmig.2015.05.022
Goodman GR, Hunter JG (1991) Results of laparoscopic cholecystectomy in a university hospital. Am J Surg 162(6):576–579
pubmed: 1670228 doi: 10.1016/0002-9610(91)90112-Q
Voitk AJ, Tsao SG, Ignatius S (2001) The tail of the learning curve for laparoscopic cholecystectomy. Am J Surg 182(3):250–253
pubmed: 11587686 doi: 10.1016/S0002-9610(01)00699-7
Luna RA, Nogueira DB, Varela PS, Rodrigues Neto Ede O, Norton MJ, Ribeiro Ldo C, Peixoto AM, de Mendonça YL, Bendet I, Fiorelli RA, Dolan JP (2013) A prospective, randomized comparison of pain, inflammatory response, and short-term outcomes between single port and laparoscopic cholecystectomy. Surg Endosc 27(4):1254–1259
pubmed: 23232993 doi: 10.1007/s00464-012-2589-5
van de Graaf FW, Zaïmi I, Stassen LPS, Lange JF (2008) Safe laparoscopic cholecystectomy: a systematic review of bile duct injury prevention. Int J Surg 60:164–172
doi: 10.1016/j.ijsu.2018.11.006
Pesce A, Latteri S, Barchitta M, Portale TR, Di Stefano B, Agodi A, Russello D, Puleo S, La Greca G (2018) Near-infrared fluorescent cholangiography-real-time visualization of the biliary tree during elective laparoscopic cholecystectomy. HPB (Oxford) 20(6):538–545
doi: 10.1016/j.hpb.2017.11.013
Boogerd LSF, Handgraaf HJM, Huurman VAL, Lam HD, Mieog JSD, van der Made WJ, van de Velde CJH, Vahrmeijer AL (2017) The best approach for laparoscopic fluorescence cholangiography: overview of the literature and optimization of dose and dosing time. Surg Innov 24(4):386–396
pubmed: 28457194 pmcid: 5505227 doi: 10.1177/1553350617702311
Meillat H, Birnbaum DJ, Fara R, Mancini J, Berdah S, Bège T (2015) Do height and weight affect the feasibility of single-incision laparoscopic cholecystectomy? Surg Endosc 29(12):3594–3599
pubmed: 25759236 doi: 10.1007/s00464-015-4115-z
Buckley FP 3rd, Vassaur HE, Jupiter DC, Crosby JH, Wheeless CJ, Vassaur JL (2016) Influencing factors for port-site hernias after single-incision laparoscopy. Hernia 20(5):729–733
pubmed: 27417943 doi: 10.1007/s10029-016-1512-8
Madureira FA, Gomez CLT, Almeida EM (2018) Comparison between incidence of incisional hernia in laparoscopic cholecystectomy and by single port. Arq Bras Cir Dig 31(1):e1354
pubmed: 29947688 pmcid: 6049988 doi: 10.1590/0102-672020180001e1354

Auteurs

Rabi R Datta (RR)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Georg Dieplinger (G)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Roger Wahba (R)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Robert Kleinert (R)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Michael Thomas (M)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Florian Gebauer (F)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Lars Schiffmann (L)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Dirk L Stippel (DL)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Christiane J Bruns (CJ)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Hans F Fuchs (HF)

Department of Surgery, University of Cologne, Kerpener Str. 62, Cologne, 50937, Germany. hans-fuchs@freenet.de.

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