Impact of Setting up an "Endocarditis Team" on the Management of Infective Endocarditis.
Endocarditis Team
cardiac surgery
guidelines
infective endocarditis
multidisciplinary management
prognosis
valve disease
Journal
Open forum infectious diseases
ISSN: 2328-8957
Titre abrégé: Open Forum Infect Dis
Pays: United States
ID NLM: 101637045
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
02
05
2019
accepted:
25
06
2019
entrez:
30
10
2019
pubmed:
30
10
2019
medline:
30
10
2019
Statut:
epublish
Résumé
Infective endocarditis (IE) remains a severe disease with a high mortality rate. Therefore, guidelines encourage the setup of a multidisciplinary group in reference centers. The present study evaluated the impact of this "Endocarditis Team" (ET). We conducted a monocentric observational study at Strasbourg University Hospital, Strasbourg, France, between 2012 and 2017. The primary end point was in-hospital mortality. Secondary end points were 6-month and 1-year mortality, surgery rate, time to surgical procedure, duration of effective antibiotic therapy, length of in-hospital stay, and sequelae. We also assessed predictors of in-hospital mortality. We analyzed 391 episodes of IE. In the post-ET period, there was a nonsignificant decrease in in-hospital mortality (20.3% vs 14.7%, respectively; This multidisciplinary approach exerted a positive impact on the management of IE and should be considered in all hospitals managing IE.
Sections du résumé
BACKGROUND
BACKGROUND
Infective endocarditis (IE) remains a severe disease with a high mortality rate. Therefore, guidelines encourage the setup of a multidisciplinary group in reference centers. The present study evaluated the impact of this "Endocarditis Team" (ET).
METHODS
METHODS
We conducted a monocentric observational study at Strasbourg University Hospital, Strasbourg, France, between 2012 and 2017. The primary end point was in-hospital mortality. Secondary end points were 6-month and 1-year mortality, surgery rate, time to surgical procedure, duration of effective antibiotic therapy, length of in-hospital stay, and sequelae. We also assessed predictors of in-hospital mortality.
RESULTS
RESULTS
We analyzed 391 episodes of IE. In the post-ET period, there was a nonsignificant decrease in in-hospital mortality (20.3% vs 14.7%, respectively;
CONCLUSIONS
CONCLUSIONS
This multidisciplinary approach exerted a positive impact on the management of IE and should be considered in all hospitals managing IE.
Identifiants
pubmed: 31660397
doi: 10.1093/ofid/ofz308
pii: ofz308
pmc: PMC6735925
doi:
Types de publication
Journal Article
Langues
eng
Pagination
ofz308Informations de copyright
© The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
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