Screening and Phenotypical Characterization of

Animals Anthelmintics / pharmacology Crystallography, X-Ray Drug Discovery / methods Female High-Throughput Screening Assays Histone Deacetylase Inhibitors / isolation & purification Male Mice Molecular Docking Simulation Phenotype Schistosoma mansoni / drug effects Structure-Activity Relationship
Schistosoma mansoni SmHDAC8 biological characterization hHDAC8 histone deacetylase inhibitors screening

Journal

ACS infectious diseases
ISSN: 2373-8227
Titre abrégé: ACS Infect Dis
Pays: United States
ID NLM: 101654580

Informations de publication

Date de publication:
10 01 2020
Historique:
pubmed: 31 10 2019
medline: 15 12 2020
entrez: 31 10 2019
Statut: ppublish

Résumé

Schistosomiasis (also known as bilharzia) is a neglected tropical disease caused by platyhelminths of the genus

Identifiants

DOI: 10.1021/acsinfecdis.9b00224 PMID: 31661956
pubmed: 31661956
doi: 10.1021/acsinfecdis.9b00224
doi:

Substances chimiques

Anthelmintics 0
Histone Deacetylase Inhibitors 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

100-113

Auteurs

Fulvio Saccoccia (F)

Institute of Biochemistry and Cell Biology (IBBC) , National Research Council (CNR) , Campus A. Buzzati-Traverso, via E. Ramarini 32 , 00015 Monterotondo ( Rome ), Italy.

Margherita Brindisi (M)

Department of Excellence of Pharmacy , University of Napoli Federico II , via D. Montesano 49 , 80131 Naples , Italy.
ORCID: 0000-0001-9119-3773

Roberto Gimmelli (R)

Institute of Biochemistry and Cell Biology (IBBC) , National Research Council (CNR) , Campus A. Buzzati-Traverso, via E. Ramarini 32 , 00015 Monterotondo ( Rome ), Italy.

Nicola Relitti (N)

Department of Excellence of Biotechnology, Chemistry and Pharmacy , University of Siena , via Aldo Moro 2 , 53100 , Siena , Italy.
ORCID: 0000-0001-9783-8966

Alessandra Guidi (A)

Institute of Biochemistry and Cell Biology (IBBC) , National Research Council (CNR) , Campus A. Buzzati-Traverso, via E. Ramarini 32 , 00015 Monterotondo ( Rome ), Italy.

A Prasanth Saraswati (AP)

Department of Excellence of Biotechnology, Chemistry and Pharmacy , University of Siena , via Aldo Moro 2 , 53100 , Siena , Italy.

Caterina Cavella (C)

Department of Excellence of Biotechnology, Chemistry and Pharmacy , University of Siena , via Aldo Moro 2 , 53100 , Siena , Italy.

Simone Brogi (S)

Department of Excellence of Biotechnology, Chemistry and Pharmacy , University of Siena , via Aldo Moro 2 , 53100 , Siena , Italy.
Department of Pharmacy , University of Pisa , via Bonanno 6 , 56126 , Pisa , Italy.
ORCID: 0000-0001-9375-6242

Giulia Chemi (G)

Department of Excellence of Biotechnology, Chemistry and Pharmacy , University of Siena , via Aldo Moro 2 , 53100 , Siena , Italy.
ORCID: 0000-0002-3868-6752

Stefania Butini (S)

Department of Excellence of Biotechnology, Chemistry and Pharmacy , University of Siena , via Aldo Moro 2 , 53100 , Siena , Italy.

Giuliana Papoff (G)

Institute of Biochemistry and Cell Biology (IBBC) , National Research Council (CNR) , Campus A. Buzzati-Traverso, via E. Ramarini 32 , 00015 Monterotondo ( Rome ), Italy.

Johanna Senger (J)

Institute of Pharmaceutical Sciences , University of Freiburg , Albertstraße 25 , 79104 Freiburg , Germany.

Daniel Herp (D)

Institute of Pharmaceutical Sciences , University of Freiburg , Albertstraße 25 , 79104 Freiburg , Germany.

Manfred Jung (M)

Institute of Pharmaceutical Sciences , University of Freiburg , Albertstraße 25 , 79104 Freiburg , Germany.
ORCID: 0000-0002-6361-7716

Giuseppe Campiani (G)

Department of Excellence of Biotechnology, Chemistry and Pharmacy , University of Siena , via Aldo Moro 2 , 53100 , Siena , Italy.
ORCID: 0000-0001-5295-9529

Sandra Gemma (S)

Department of Excellence of Biotechnology, Chemistry and Pharmacy , University of Siena , via Aldo Moro 2 , 53100 , Siena , Italy.
ORCID: 0000-0002-8313-2417

Giovina Ruberti (G)

Institute of Biochemistry and Cell Biology (IBBC) , National Research Council (CNR) , Campus A. Buzzati-Traverso, via E. Ramarini 32 , 00015 Monterotondo ( Rome ), Italy.
ORCID: 0000-0003-2367-9709

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis.

Hiu Yee Liu, Ashley A Eso, Nathan Cook et al.
1.00
Humans Meals Time Factors Female Adult

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Screening and Phenotypical Characterization of
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Anthelminthiques › Screening and Phenotypical Characterization of
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › Screening and Phenotypical Characterization of
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Screening and Phenotypical Characterization of
questionsmedicales.fr › Techniques d'investigation › Tests de criblage à haut débit › Screening and Phenotypical Characterization of
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de désacétylase d'histone › Screening and Phenotypical Characterization of
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Screening and Phenotypical Characterization of
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Screening and Phenotypical Characterization of
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Screening and Phenotypical Characterization of
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Helminthes › Plathelminthes › Trematoda › Schistosomatidae › Schistosoma › Schistosoma mansoni › Screening and Phenotypical Characterization of
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Screening and Phenotypical Characterization of