Frequency of Signs and Symptoms in Persons With Asthma.


Journal

Respiratory care
ISSN: 1943-3654
Titre abrégé: Respir Care
Pays: United States
ID NLM: 7510357

Informations de publication

Date de publication:
Feb 2020
Historique:
pubmed: 31 10 2019
medline: 15 12 2020
entrez: 31 10 2019
Statut: ppublish

Résumé

Signs and symptoms of asthma are well established; however, no study has been performed to rank them. Therefore, we performed this systematic review and meta-analysis to determine the pooled frequencies of different signs and symptoms of asthma in subjects age ≥ 14 y to develop a patient-specific questionnaire. Specific search queries were developed to include records published in Embase, PubMed, Cochrane Library, and Google Scholar, until November 2016. We planned to include randomized controlled trials (RCTs) and observational studies for determining the pooled proportions of signs and symptoms and association between combination of symptoms and asthma severity in subjects age ≥ 14 y. The quality assessment was performed using 3 parameters: reported number or percentage of subjects with asthma symptoms, respiratory disorder history, and method for data collection. Of the 4,939 records retrieved, 67 observational studies ( Asthma severity was dependent on variety of symptoms, consisting mostly of wheezing, breathlessness, chest tightness, and cough. On the basis of our analysis, we recommend a combination of symptoms be included in diagnostic-based questionnaires to aid early diagnosis.

Sections du résumé

BACKGROUND BACKGROUND
Signs and symptoms of asthma are well established; however, no study has been performed to rank them. Therefore, we performed this systematic review and meta-analysis to determine the pooled frequencies of different signs and symptoms of asthma in subjects age ≥ 14 y to develop a patient-specific questionnaire.
METHODS METHODS
Specific search queries were developed to include records published in Embase, PubMed, Cochrane Library, and Google Scholar, until November 2016. We planned to include randomized controlled trials (RCTs) and observational studies for determining the pooled proportions of signs and symptoms and association between combination of symptoms and asthma severity in subjects age ≥ 14 y. The quality assessment was performed using 3 parameters: reported number or percentage of subjects with asthma symptoms, respiratory disorder history, and method for data collection.
RESULTS RESULTS
Of the 4,939 records retrieved, 67 observational studies (
CONCLUSIONS CONCLUSIONS
Asthma severity was dependent on variety of symptoms, consisting mostly of wheezing, breathlessness, chest tightness, and cough. On the basis of our analysis, we recommend a combination of symptoms be included in diagnostic-based questionnaires to aid early diagnosis.

Identifiants

pubmed: 31662445
pii: respcare.06714
doi: 10.4187/respcare.06714
doi:

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

252-264

Informations de copyright

Copyright © 2020 by Daedalus Enterprises.

Auteurs

Zhengguang He (Z)

Respiratory Center of Suining Central Hospital, Sichuan, China.

Juntao Feng (J)

Respiratory Medicine, Xiangya Hospital, Central South University, Hunan, China.

Junbo Xia (J)

Respiratory Medicine, Hangzhou 1st People's Hospital affiliated with Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Qingguo Wu (Q)

Respiratory Medicine, Zhejiang Traditional Chinese Medicine University 2nd Affiliated Hospital, Hangzhou, Zhejiang, China.

Hong Yang (H)

Respiratory Medicine, Huangdao District Traditional Chinese Medicine Hospital, Shandong, China.

Qianli Ma (Q)

Institution of Respiratory Disease, Xinqiao Hospital of 3rd Military Medical University, Chongqing, China. cqmql@163.com.

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