What is the remaining status of adaptive servo-ventilation? The results of a real-life multicenter study (OTRLASV-study) : Adaptive servo-ventilation in real-life conditions.
Adaptive servo-ventilation
CPAP
Central sleep apnea
Chronic heart failure
Obstructive sleep apnea
Sleep-disordered breathing
Treatment emergent central sleep apnea
Journal
Respiratory research
ISSN: 1465-993X
Titre abrégé: Respir Res
Pays: England
ID NLM: 101090633
Informations de publication
Date de publication:
29 Oct 2019
29 Oct 2019
Historique:
received:
01
08
2019
accepted:
17
10
2019
entrez:
31
10
2019
pubmed:
31
10
2019
medline:
24
4
2020
Statut:
epublish
Résumé
As a consequence of the increased mortality observed in the SERVE-HF study, many questions concerning the safety and rational use of ASV in other indications emerged. The aim of this study was to describe the clinical characteristics of ASV-treated patients in real-life conditions. The OTRLASV-study is a prospective, 5-centre study including patients who underwent ASV-treatment for at least 1 year. Patients were consecutively included in the study during the annual visit imposed for ASV-reimbursement renewal. 177/214 patients were analysed (87.57% male) with a median (IQ In real-life conditions, ASV-treatment is often associated with high cardiac comorbidities and high compliance. Future research should assess how regular night monitoring may optimize devices settings and patient management. The OTRLASV study is registered on ClinicalTrials.gov (Identifier: NCT02429986 ) on 1 April 2015.
Sections du résumé
BACKGROUNDS
BACKGROUND
As a consequence of the increased mortality observed in the SERVE-HF study, many questions concerning the safety and rational use of ASV in other indications emerged. The aim of this study was to describe the clinical characteristics of ASV-treated patients in real-life conditions.
METHODS
METHODS
The OTRLASV-study is a prospective, 5-centre study including patients who underwent ASV-treatment for at least 1 year. Patients were consecutively included in the study during the annual visit imposed for ASV-reimbursement renewal.
RESULTS
RESULTS
177/214 patients were analysed (87.57% male) with a median (IQ
CONCLUSIONS
CONCLUSIONS
In real-life conditions, ASV-treatment is often associated with high cardiac comorbidities and high compliance. Future research should assess how regular night monitoring may optimize devices settings and patient management.
TRIAL REGISTRATION
BACKGROUND
The OTRLASV study is registered on ClinicalTrials.gov (Identifier: NCT02429986 ) on 1 April 2015.
Identifiants
pubmed: 31665026
doi: 10.1186/s12931-019-1221-9
pii: 10.1186/s12931-019-1221-9
pmc: PMC6819598
doi:
Banques de données
ClinicalTrials.gov
['NCT02429986']
Types de publication
Journal Article
Multicenter Study
Observational Study
Pragmatic Clinical Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
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