Carcinogenic potential of fluorinated estrogens in mammary tumorigenesis.

Animals Breast Neoplasms / chemically induced Cell Transformation, Neoplastic / chemically induced Estradiol / analogs & derivatives Female Organ Size / drug effects Rats, Inbred ACI Risk Assessment Uterus / drug effects
DNA adduct Estrogen Fluorination Mammary tumor Uterotrophic activity

Journal

Toxicology letters
ISSN: 1879-3169
Titre abrégé: Toxicol Lett
Pays: Netherlands
ID NLM: 7709027

Informations de publication

Date de publication:
Jan 2020
Historique:
received: 04 08 2019
revised: 18 10 2019
accepted: 18 10 2019
pubmed: 2 11 2019
medline: 26 11 2019
entrez: 1 11 2019
Statut: ppublish

Résumé

Fluorination preventing metabolic hydroxylation of 17β-estradiol (E

Identifiants

DOI: 10.1016/j.toxlet.2019.10.015 PMID: 31669098
pubmed: 31669098
pii: S0378-4274(19)30334-0
doi: 10.1016/j.toxlet.2019.10.015
pii:
doi:

Substances chimiques

2-fluoroestradiol 16205-32-6
4-fluoroestradiol 1881-37-4
Estradiol 4TI98Z838E

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

99-103

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Yoshinori Okamoto (Y)

Faculty of Pharmacy, Meijo University, Yagotoyama, Nagoya 468-8503, Japan.

Hideto Jinno (H)

Faculty of Pharmacy, Meijo University, Yagotoyama, Nagoya 468-8503, Japan.

Shinji Itoh (S)

Faculty of Pharmaceutical Sciences, Hokkaido University of Science, Maeda, Sapporo, Hokkaido 006-8585, Japan.

Shinya Shibutani (S)

Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, New York 11794-8651, USA. Electronic address: shinya.shibutani@stonybrook.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Carcinogenic potential of fluorinated...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Carcinogenic potential of fluorinated...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Carcinogenèse › Transformation cellulaire néoplasique › Carcinogenic potential of fluorinated...
questionsmedicales.fr › Hormones gonadiques › Hormones sexuelles stéroïdiennes › Congénères de l'oestradiol › Oestradiol › Carcinogenic potential of fluorinated...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Taille d'organe › Carcinogenic potential of fluorinated...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Lignées consanguines de rats › Rats de lignée ACI › Carcinogenic potential of fluorinated...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Appréciation des risques › Carcinogenic potential of fluorinated...
questionsmedicales.fr › Appareil urogénital › Système génital › Système génital de la femme › Utérus › Carcinogenic potential of fluorinated...