Glucagon Regulation of Energy Expenditure.
FGF21
brown adipose tissue
energy expenditure
glucagon
obesity
pharmacology
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
30 Oct 2019
30 Oct 2019
Historique:
received:
30
09
2019
revised:
23
10
2019
accepted:
24
10
2019
entrez:
2
11
2019
pubmed:
2
11
2019
medline:
24
3
2020
Statut:
epublish
Résumé
Glucagon's ability to increase energy expenditure has been known for more than 60 years, yet the mechanisms underlining glucagon's thermogenic effect still remain largely elusive. Over the last years, significant efforts were directed to unravel the physiological and cellular underpinnings of how glucagon regulates energy expenditure. In this review, we summarize the current knowledge on how glucagon regulates systems metabolism with a special emphasis on its acute and chronic thermogenic effects.
Identifiants
pubmed: 31671603
pii: ijms20215407
doi: 10.3390/ijms20215407
pmc: PMC6862306
pii:
doi:
Substances chimiques
Glucagon
9007-92-5
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIDDK NIH HHS
ID : P30 DK056336
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK079626
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK112934
Pays : United States
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