[Cutaneous leishmaniasis of the vermilion border of the upper lip extending to the oral mucosa].
Leishmaniose cutanée du vermillon avec atteinte muqueuse de la lèvre supérieure.
Atteinte muqueuse
Fluconazole
L. tropica
Leishmaniasis
Leishmaniose cutanée
Lip
Mucosal involvement
Journal
Annales de dermatologie et de venereologie
ISSN: 0151-9638
Titre abrégé: Ann Dermatol Venereol
Pays: France
ID NLM: 7702013
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
received:
13
05
2018
revised:
29
03
2019
accepted:
17
09
2019
pubmed:
2
11
2019
medline:
21
11
2020
entrez:
2
11
2019
Statut:
ppublish
Résumé
Cutaneous leishmaniasis is endemic in Morocco. Mucosal involvement is rare. We report a case in Morocco of cutaneous leishmaniasis of the vermilion border of the upper lip extending to the oral mucosa due to Leishmania tropica. A 15-year-old girl was seen with 2 ulcerated lesions, present for 4 months, situated on the left cheek and vermilion border and extending to the oral mucosa. The diagnosis of leishmaniasis was confirmed by direct examination revealing high numbers of Leishmania amastigotes. Culture of the offending organism in NNN medium and isoenzymatic characterization resulted in identification of L. tropica. Treatment with meglumine antimoniate (Glucantime) was ineffective. The outcome was good after treatment with fluconazole. In Morocco, cutaneous leishmaniasis with mucosal involvement is rare, and usually develops as a complication of cutaneous leishmaniasis via direct extension.
Sections du résumé
BACKGROUND
BACKGROUND
Cutaneous leishmaniasis is endemic in Morocco. Mucosal involvement is rare. We report a case in Morocco of cutaneous leishmaniasis of the vermilion border of the upper lip extending to the oral mucosa due to Leishmania tropica.
PATIENTS AND METHODS
METHODS
A 15-year-old girl was seen with 2 ulcerated lesions, present for 4 months, situated on the left cheek and vermilion border and extending to the oral mucosa. The diagnosis of leishmaniasis was confirmed by direct examination revealing high numbers of Leishmania amastigotes. Culture of the offending organism in NNN medium and isoenzymatic characterization resulted in identification of L. tropica. Treatment with meglumine antimoniate (Glucantime) was ineffective. The outcome was good after treatment with fluconazole.
CONCLUSION
CONCLUSIONS
In Morocco, cutaneous leishmaniasis with mucosal involvement is rare, and usually develops as a complication of cutaneous leishmaniasis via direct extension.
Identifiants
pubmed: 31672326
pii: S0151-9638(19)30924-X
doi: 10.1016/j.annder.2019.09.600
pii:
doi:
Substances chimiques
Meglumine Antimoniate
75G4TW236W
Fluconazole
8VZV102JFY
Types de publication
Case Reports
Langues
fre
Sous-ensembles de citation
IM
Pagination
116-118Informations de copyright
Copyright © 2019 Elsevier Masson SAS. All rights reserved.