The characteristics of the patients with radiologically severe cervical ossification of the posterior longitudinal ligament of the spine: A CT-based multicenter cross-sectional study.

Adult Aged Aged, 80 and over Cervical Vertebrae / diagnostic imaging Cross-Sectional Studies Female Humans Japan Male Middle Aged Ossification of Posterior Longitudinal Ligament / diagnostic imaging Tomography, X-Ray Computed

Journal

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
ISSN: 1436-2023
Titre abrégé: J Orthop Sci
Pays: Japan
ID NLM: 9604934

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 24 05 2019
revised: 06 08 2019
accepted: 30 09 2019
pubmed: 2 11 2019
medline: 14 7 2021
entrez: 2 11 2019
Statut: ppublish

Résumé

Ossification of the posterior longitudinal ligament of the spine (OPLL) is characterized by heterotopic bone formation in the posterior longitudinal ligament of the spine. We know that the size and distribution of the ossified lesions in patients with OPLL are different in each case. However, the characteristics of the patients with radiologically severe cervical OPLL remain unknown. The participants of our study were symptomatic patients with cervical OPLL who were diagnosed by standard radiographs of the cervical spine. Whole-spine CT data and demographic data such as age and sex were obtained from 20 institutions belonging to the Japanese Multicenter Research Organization for Ossification of the Spinal Ligament. According to the number of the levels involved by OPLL, we stratified the patients into two subgroups: severe group (S-group) and non-severe group (NS-group) to delineate the characteristics of radiologically severe patients with cervical OPLL. We also evaluated the most compressed level and the degree of occupying ratio of cervical spinal canal by OPLL at the most compressed level. A total of 234 patients with a mean age of 65 years were recruited. The S-group consisted of 48 patients (21%, 12 females and 36 males) and the NS-group consisted of 92 patients (79%, 22 females and 70 males). The mean age of males in the S-group (68 years old) was significantly higher than that of males in the NS-group (64 years old); however there was no significant difference in the mean age in females between the S-group (69 years old) and the NS-group (66 years old). No significant difference of body mass index, ossification of the nuchal ligament-positivity and presence of diabetes mellitus were found between the S- and the NS-group. It is likely that the manner of extension of cervical OPLL is different between male and female patients.

Sections du résumé

BACKGROUND BACKGROUND
Ossification of the posterior longitudinal ligament of the spine (OPLL) is characterized by heterotopic bone formation in the posterior longitudinal ligament of the spine. We know that the size and distribution of the ossified lesions in patients with OPLL are different in each case. However, the characteristics of the patients with radiologically severe cervical OPLL remain unknown.
METHODS METHODS
The participants of our study were symptomatic patients with cervical OPLL who were diagnosed by standard radiographs of the cervical spine. Whole-spine CT data and demographic data such as age and sex were obtained from 20 institutions belonging to the Japanese Multicenter Research Organization for Ossification of the Spinal Ligament. According to the number of the levels involved by OPLL, we stratified the patients into two subgroups: severe group (S-group) and non-severe group (NS-group) to delineate the characteristics of radiologically severe patients with cervical OPLL. We also evaluated the most compressed level and the degree of occupying ratio of cervical spinal canal by OPLL at the most compressed level.
RESULTS RESULTS
A total of 234 patients with a mean age of 65 years were recruited. The S-group consisted of 48 patients (21%, 12 females and 36 males) and the NS-group consisted of 92 patients (79%, 22 females and 70 males). The mean age of males in the S-group (68 years old) was significantly higher than that of males in the NS-group (64 years old); however there was no significant difference in the mean age in females between the S-group (69 years old) and the NS-group (66 years old). No significant difference of body mass index, ossification of the nuchal ligament-positivity and presence of diabetes mellitus were found between the S- and the NS-group.
CONCLUSIONS CONCLUSIONS
It is likely that the manner of extension of cervical OPLL is different between male and female patients.

Identifiants

DOI: 10.1016/j.jos.2019.09.018 PMID: 31672380
pubmed: 31672380
pii: S0949-2658(19)30313-6
doi: 10.1016/j.jos.2019.09.018
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

746-750

Informations de copyright

Copyright © 2019 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest None.

Auteurs

Kanji Mori (K)

Department of Orthopaedic Surgery, Shiga University of Medical Science, Tsukinowa-cho, Seta, Otsu, Shiga, 520-2192, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. Electronic address: kanchi@belle.shiga-med.ac.jp.

Toshitaka Yoshii (T)

Department of Orthopedic Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Takashi Hirai (T)

Department of Orthopedic Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Narihito Nagoshi (N)

Department of Orthopedic Surgery, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Kazuhiro Takeuchi (K)

Department of Orthopedic Surgery, National Hospital Organization Okayama Medical Center, 1711-1 Tamasu, Okayama, Okayama, 701-1154, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Shuta Ushio (S)

Department of Orthopedic Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Akio Iwanami (A)

Department of Orthopedic Surgery, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

Tsuyoshi Yamada (T)

Department of Orthopedic Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Shoji Seki (S)

Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama, Toyama, 930-0194, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Takashi Tsuji (T)

Department of Orthopedic Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Kanehiro Fujiyoshi (K)

Department of Orthopedic Surgery, National Hospital Organization Murayama Medical Center, 2-37-1 Gakuen, Musashimurayama, Tokyo, 208-0011, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Mitsuru Furukawa (M)

Department of Orthopedic Surgery, Shizuoka City Shimizu Hospital, 1231 Miyakami, Shimizu-ku, Shizuoka, 424-8636, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Soraya Nishimura (S)

Department of Orthopedic Surgery, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan; Department of Orthopedic Surgery, Keiyu Hospital, 3-7-3 Minatomirai, Nishi-ku, Yokohama, Kanagawa, 220-0012, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Kanichiro Wada (K)

Department of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, 53 Honcho, Hirosaki, Aomori, 036-8203, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Takeo Furuya (T)

Department of Orthopaedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-0856, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Yukihiro Matsuyama (Y)

Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, Shizuoka, 431-3125, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Tomohiko Hasegawa (T)

Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, Shizuoka, 431-3125, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Katsushi Takeshita (K)

Department of Orthopedics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochugi, 329-0498, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Atsushi Kimura (A)

Department of Orthopedics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochugi, 329-0498, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Masahiko Abematsu (M)

Department of Orthopedic Surgery, Graduate School of Medicine and Dental Science, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, Kagoshima, 890-8520, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Hirotaka Haro (H)

Department of Orthopedic Surgery, University of Yamanashi, 1110 Shimokato, Chuo-ku, Yamanashi, 409-3898, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Tetsuro Ohba (T)

Department of Orthopedic Surgery, University of Yamanashi, 1110 Shimokato, Chuo-ku, Yamanashi, 409-3898, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Masahiko Watanabe (M)

Department of Orthopedic Surgery, Surgical Science, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1143, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Hiroyuki Katoh (H)

Department of Orthopedic Surgery, Surgical Science, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1143, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Kei Watanabe (K)

Department of Orthopedic Surgery, Niigata University Medicine and Dental General Hospital, 1-754 Asahimachidori, Chuo-ku, Niigata, Niigata, 951-8520, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Hiroshi Ozawa (H)

Department of Orthopedic Surgery, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aobaku, Sendai, Miyagi, 981-8558, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Haruo Kanno (H)

Department of Orthopaedic Surgery, Tohoku University School of Medicine, 1-1 Seiryomachi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Shiro Imagama (S)

Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumaicho, Showa-ku, Nagoya, Aichi, 466-0065, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Kei Ando (K)

Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumaicho, Showa-ku, Nagoya, Aichi, 466-0065, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Shunsuke Fujibayashi (S)

Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, Kyoto, 606-8507, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Masao Koda (M)

Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Masashi Yamazaki (M)

Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Morio Matsumoto (M)

Department of Orthopedic Surgery, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

Masaya Nakamura (M)

Department of Orthopedic Surgery, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

Atsushi Okawa (A)

Department of Orthopedic Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Yoshiharu Kawaguchi (Y)

Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama, Toyama, 930-0194, Japan; Japanese Organization of the Study for Ossification of Spinal Ligament (JOSL), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › The characteristics of the patients with...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › The characteristics of the patients with...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Sujet âgé de 80 ans ou plus › The characteristics of the patients with...
questionsmedicales.fr › Appareil locomoteur › Squelette › Rachis › Vertèbres cervicales › The characteristics of the patients with...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études transversales › The characteristics of the patients with...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The characteristics of the patients with...
questionsmedicales.fr › Régions géographiques › Iles › Japon › The characteristics of the patients with...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › The characteristics of the patients with...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Ossification hétérotopique › Ossification du ligament longitudinal postérieur › The characteristics of the patients with...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Tomographie à rayons X › Tomodensitométrie › The characteristics of the patients with...