Comparison of the linking arm effect on the biological performance of a CD31 agonist directly grafted on L605 CoCr alloy by a plasma-based multistep strategy.
Alloys
/ chemistry
Cell Adhesion
Cell Proliferation
Cell Survival
Chromium
/ chemistry
Coated Materials, Biocompatible
/ chemistry
Cobalt
/ chemistry
Human Umbilical Vein Endothelial Cells
Humans
Materials Testing
Peptides
/ chemistry
Plasma Gases
/ chemistry
Platelet Endothelial Cell Adhesion Molecule-1
/ agonists
Stents
Surface Properties
Journal
Biointerphases
ISSN: 1559-4106
Titre abrégé: Biointerphases
Pays: United States
ID NLM: 101275679
Informations de publication
Date de publication:
01 11 2019
01 11 2019
Historique:
entrez:
3
11
2019
pubmed:
5
11
2019
medline:
10
4
2020
Statut:
epublish
Résumé
Stents are cardiovascular implants deployed on atherosclerotic arteries that aid in reopening, sustaining, and avoiding their collapse. Nevertheless, postimplantation complications exist, and the risk of the renewal of the plaque subsists. Therefore, enhanced properties are mandatory requirements for clinics. For that purpose, a novel approach allowing the direct-grafting of bioactive molecules on cobalt-chromium devices (L605) has been developed. This original strategy involves the direct plasma functionalization of metallic surfaces with primary amines (-NH
Substances chimiques
Alloys
0
Coated Materials, Biocompatible
0
PECAM1 protein, human
0
Peptides
0
Plasma Gases
0
Platelet Endothelial Cell Adhesion Molecule-1
0
Chromium
0R0008Q3JB
Cobalt
3G0H8C9362
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM