Culture Conversion at 6 Months in Patients Receiving Delamanid-containing Regimens for the Treatment of Multidrug-resistant Tuberculosis.


Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
11 07 2020
Historique:
received: 10 07 2019
accepted: 30 10 2019
pubmed: 5 11 2019
medline: 13 3 2021
entrez: 3 11 2019
Statut: ppublish

Résumé

Delamanid should be effective against highly resistant strains of Mycobacteriumtuberculosis, but uptake has been slow globally. In the endTB (expand new drug markets for TB) Observational Study, which enrolled a large, heterogeneous cohorts of patients receiving delamanid as part of a multidrug regimen, 80% of participants experienced sputum culture conversion within 6 months. Clinical Trials Registration. NCT02754765.

Identifiants

pubmed: 31676905
pii: 5611120
doi: 10.1093/cid/ciz1084
doi:

Substances chimiques

Antitubercular Agents 0
Nitroimidazoles 0
OPC-67683 0
Oxazoles 0

Banques de données

ClinicalTrials.gov
['NCT02754765']

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

415-418

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Auteurs

Kwonjune J Seung (KJ)

Partners In Health, Boston, Massachusetts, USA.

Palwasha Khan (P)

Interactive Research and Development, Karachi, Pakistan.

Molly F Franke (MF)

Department of Global Health and Social Medicine, Harvard Medical School and Partners In Health, Boston, Massachusetts, USA.

Saman Ahmed (S)

Interactive Research and Development, Karachi, Pakistan.

Stalbek Aiylchiev (S)

Médecins Sans Frontières, Kyrgyzstan.

Manzur Alam (M)

Interactive Research and Development, Dhaka, Bangladesh.

Fauziah Asnely Putri (FA)

Interactive Research and Development, Indonesia.

Mathieu Bastard (M)

Field Epidemiology Department, Epicentre, Paris, France.

Wisny Docteur (W)

Zanmi Lasante, Port-Au-Prince, Haiti.

Gary Gottlieb (G)

Partners In Health, Boston, Massachusetts, USA.

Catherine Hewison (C)

Medical Department, Médecins Sans Frontières, Paris, France.

Shirajul Islam (S)

Interactive Research and Development, Dhaka, Bangladesh.

Naira Khachatryan (N)

Médecins Sans Frontières, Armenia.

Tinatin Kotrikadze (T)

Médecins Sans Frontières, Georgia.

Uzma Khan (U)

Interactive Research and Development, Dubai, United Arab Emirates.

Andargachew Kumsa (A)

Partners In Health, Addis Ababa, Ethiopia.

Leonid Lecca (L)

Socios En Salud, Lima, Peru.

Yoseph Melaku Tassew (YM)

Médecins Sans Frontières, Belarus.

Nara Melikyan (N)

Médecins Sans Frontières, Belarus.

Ye Yint Naing (YY)

Médecins Sans Frontières, Myanmar.

Lawrence Oyewusi (L)

Partners In Health, Maseru, Lesotho.

Michael Rich (M)

Partners In Health, Boston, Massachusetts, USA.

Stephen Wanjala (S)

Médecins Sans Frontières, Kenya.

Askar Yedilbayev (A)

Partners In Health, Boston, Massachusetts, USA.

Helena Huerga (H)

Field Epidemiology Department, Epicentre, Paris, France.

Carole D Mitnick (CD)

Department of Global Health and Social Medicine, Harvard Medical School and Partners In Health, Boston, Massachusetts, USA.

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Classifications MeSH