Molecularly Imprinted Polymers for Cell Recognition.


Journal

Trends in biotechnology
ISSN: 1879-3096
Titre abrégé: Trends Biotechnol
Pays: England
ID NLM: 8310903

Informations de publication

Date de publication:
04 2020
Historique:
received: 23 07 2019
revised: 27 09 2019
accepted: 03 10 2019
pubmed: 5 11 2019
medline: 16 7 2021
entrez: 4 11 2019
Statut: ppublish

Résumé

Since their conception 50 years ago, molecularly imprinted polymers (MIPs) have seen extensive development both in terms of synthetic routes and applications. Cells are perhaps the most challenging target for molecular imprinting. Although early work was based almost entirely around microprinting methods, recent developments have shifted towards epitope imprinting to generate MIP nanoparticles (NPs). Simultaneously, the development of techniques such as solid phase MIP synthesis has solved many historic issues of MIP production. This review briefly describes various approaches used in cell imprinting with a focus on applications of the created materials in imaging, drug delivery, diagnostics, and tissue engineering.

Identifiants

pubmed: 31677857
pii: S0167-7799(19)30235-5
doi: 10.1016/j.tibtech.2019.10.002
pii:
doi:

Substances chimiques

Epitopes 0
Molecularly Imprinted Polymers 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

368-387

Subventions

Organisme : National Centre for the Replacement, Refinement and Reduction of Animals in Research
ID : NC/L002175/1
Pays : United Kingdom
Organisme : National Centre for the Replacement, Refinement and Reduction of Animals in Research
ID : NC/L002175/1
Pays : United Kingdom

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Stanislav Piletsky (S)

Department of Chemistry, Imperial College, London SW7 2AZ, UK.

Francesco Canfarotta (F)

MIP Diagnostics, Colworth Park, Sharnbrook, Bedford MK44 1LQ, UK.

Alessandro Poma (A)

University College London (UCL) Eastman Dental Institute, London WC1X 8LD, UK.

Alessandra Maria Bossi (AM)

Department of Biotechnology, University of Verona, 37134 Verona, Italy. Electronic address: alessandramaria.bossi@univr.it.

Sergey Piletsky (S)

Department of Chemistry, College of Science and Engineering, University of Leicester, Leicester LE1 7RH, UK.

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Classifications MeSH