Co-ingestion of Antioxidant Drinks With an Unhealthy Challenge Meal Fails to Prevent Post-prandial Endothelial Dysfunction: An Open-Label, Crossover Study in Older Overweight Volunteers.

antioxidants endothelial function flow-mediated dilatation green tea orange juice polyphenols red wine

Journal

Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006

Informations de publication

Date de publication:
2019
Historique:
received: 14 08 2019
accepted: 25 09 2019
entrez: 5 11 2019
pubmed: 5 11 2019
medline: 5 11 2019
Statut: epublish

Résumé

Eating a high calorie meal is known to induce endothelial dysfunction and it is reported that consuming drinks rich in antioxidants may be protective against this. In this study we assessed the effects of three antioxidant drinks with considerable disparity in their antioxidant content on endothelial function. Seven apparently healthy overweight and older adults (BMI 25-35; mean age 57 ± 3 years; one male, six females) completed four trials in a randomized counterbalanced design. Water (control), orange juice, green tea, or red wine were consumed with a high calorie meal (>900 kcal). Endothelial function was measured by flow-mediated dilatation immediately before (fasted, baseline) and 2 h after the meal. Blood samples were also obtained for lipid and glucose analysis, plasma nitrite (

Identifiants

pubmed: 31681007
doi: 10.3389/fphys.2019.01293
pmc: PMC6797614
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1293

Informations de copyright

Copyright © 2019 Muggeridge, Goszcz, Treweeke, Adamson, Hickson, Crabtree and Megson.

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Auteurs

David J Muggeridge (DJ)

Free Radical Research Facility, Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.
Active Health Exercise Laboratory, Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.

Katarzyna Goszcz (K)

Free Radical Research Facility, Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.

Andrew Treweeke (A)

Free Radical Research Facility, Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.

Janet Adamson (J)

Free Radical Research Facility, Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.

Kirsty Hickson (K)

Free Radical Research Facility, Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.
Active Health Exercise Laboratory, Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.

Daniel Crabtree (D)

Active Health Exercise Laboratory, Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.

Ian L Megson (IL)

Free Radical Research Facility, Division of Biomedical Sciences, Institute of Health Research and Innovation, University of the Highlands and Islands, Inverness, United Kingdom.

Classifications MeSH